Cargando…

DNA replication initiation factor RECQ4 possesses a role in antagonizing DNA replication initiation

Deletion of the conserved C-terminus of the Rothmund-Thomson syndrome helicase RECQ4 is highly tumorigenic. However, while the RECQ4 N-terminus is known to facilitate DNA replication initiation, the function of its C-terminus remains unclear. Using an unbiased proteomic approach, we identify an inte...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Xiaohua, Chang, Chou-Wei, Li, Min, Omabe, Kenneth, Le, Nhung, Chen, Yi-Hsuan, Liang, Feng, Liu, Yilun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985596/ https://www.ncbi.nlm.nih.gov/pubmed/36871012 http://dx.doi.org/10.1038/s41467-023-36968-1

Ejemplares similares

Understanding the Human RECQ5 Helicase—Connecting the Dots from DNA to Clinics
por: Mo, Chiefe, et al.
Publicado: (2023)

RECQ5: A Mysterious Helicase at the Interface of DNA Replication and Transcription
por: Andrs, Martin, et al.
Publicado: (2020)

Molecular Mechanisms of the RECQ4 Pathogenic Mutations
por: Xu, Xiaohua, et al.
Publicado: (2021)

Pathogenic mutations reveal a role of RECQ4 in mitochondrial RNA:DNA hybrid formation and resolution
por: Chang, Chou-Wei, et al.
Publicado: (2020)

Loading and activation of DNA replicative helicases: the key step of initiation of DNA replication
por: Li, Yan, et al.
Publicado: (2013)

Initiation of DNA Replication: The Genomic Context
Publicado: (2004)

Control of DNA Replication Initiation by Ubiquitin
por: Hernández-Carralero, Esperanza, et al.
Publicado: (2018)

Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition
por: Berti, Matteo, et al.
Publicado: (2013)

Cell Size and the Initiation of DNA Replication in Bacteria
por: Hill, Norbert S., et al.
Publicado: (2012)

Quality control in the initiation of eukaryotic DNA replication
por: Diffley, John F. X.
Publicado: (2011)

Emerging players in the initiation of eukaryotic DNA replication
por: Shen, Zhen, et al.
Publicado: (2012)

Regulation of DNA Replication Initiation by Chromosome Structure
por: Magnan, David, et al.
Publicado: (2015)

Inhibition of DNA replication initiation by silver nanoclusters
por: Tao, Yu, et al.
Publicado: (2021)

Rapid turnover of DnaA at replication origin regions contributes to initiation control of DNA replication
por: Schenk, Katrin, et al.
Publicado: (2017)

Specificity and Function of Archaeal DNA Replication Initiator Proteins
por: Samson, Rachel Y., et al.
Publicado: (2013)

RECQ1 Promotes Stress Resistance and DNA Replication Progression Through PARP1 Signaling Pathway in Glioblastoma
por: Zhang, Jing, et al.
Publicado: (2021)

Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells
por: Kliszczak, Maciej, et al.
Publicado: (2015)

The role of CDK in the initiation step of DNA replication in eukaryotes
por: Tanaka, Seiji, et al.
Publicado: (2007)

Opposing effects of DNA on proteolysis of a replication initiator
por: Kubik, Slawomir, et al.
Publicado: (2012)

Mechanisms Governing DDK Regulation of the Initiation of DNA Replication
por: Larasati,, et al.
Publicado: (2016)

Investigating the role of Rts1 in DNA replication initiation
por: Wallis, Ana B.A., et al.
Publicado: (2018)

Initiating DNA replication: a matter of prime importance
por: Bell, Stephen D.
Publicado: (2019)

From structure to mechanism—understanding initiation of DNA replication
por: Riera, Alberto, et al.
Publicado: (2017)

Transcriptional Activity of the Bacterial Replication Initiator DnaA
por: Menikpurage, Inoka P., et al.
Publicado: (2021)

Dpb11 may function with RPA and DNA to initiate DNA replication
por: Bruck, Irina, et al.
Publicado: (2017)

Reversible lysine acetylation is involved in DNA replication initiation by regulating activities of initiator DnaA in Escherichia coli
por: Zhang, Qiufen, et al.
Publicado: (2016)

Drosophila RecQ4 Is Directly Involved in Both DNA Replication and the Response to UV Damage in S2 Cells
por: Crevel, Gilles, et al.
Publicado: (2012)

The RecQ DNA helicase Rqh1 constrains Exonuclease 1-dependent recombination at stalled replication forks
por: Osman, Fekret, et al.
Publicado: (2016)

The BRCA1 BRCT promotes antisense RNA production and double-stranded RNA formation to suppress ribosomal R-loops
por: Chang, Chou-Wei, et al.
Publicado: (2022)

Roles for DNA polymerase δ in initiating and terminating leading strand DNA replication
por: Zhou, Zhi-Xiong, et al.
Publicado: (2019)

RecQ helicase triggers a binding mode change in the SSB–DNA complex to efficiently initiate DNA unwinding
por: Mills, Maria, et al.
Publicado: (2017)

Initiation of DNA replication at the human β-globin 3′ enhancer
por: Buzina, Alla, et al.
Publicado: (2005)

Plasticity of DNA Replication Initiation in Epstein-Barr Virus Episomes
por: Norio, Paolo, et al.
Publicado: (2004)

DNA stretching by bacterial initiators promotes replication origin melting
por: Duderstadt, Karl E., et al.
Publicado: (2011)

Origin-dependent initiation of DNA replication within telomeric sequences
por: Kurth, Isabel, et al.
Publicado: (2010)

Control of Initiation of DNA Replication in Bacillus subtilis and Escherichia coli
por: Jameson, Katie H., et al.
Publicado: (2017)

Transcription shapes DNA replication initiation and termination in human cells
por: Chen, Yu-Hung, et al.
Publicado: (2018)

DNA translocation mechanism of the MCM complex and implications for replication initiation
por: Meagher, Martin, et al.
Publicado: (2019)

Transcription shapes DNA replication initiation to preserve genome integrity
por: Liu, Yang, et al.
Publicado: (2021)

Multiple mechanisms for overcoming lethal over‐initiation of DNA replication
por: Anderson, Mary E., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8a08bd2flqef5saai32rq44rd2