Self-cyclisation as a general and efficient platform for peptide and protein macrocyclisation

Macrocyclisation of proteins and peptides results in a remarkable increase in structural stability, making cyclic peptides and proteins of great interest in drug discovery—either directly as drug leads or as in the case of cyclised nanodiscs (cNDs), as tools for studies of trans-membrane receptors a...

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Detalles Bibliográficos
Autores principales: Jia, Xinying, Chin, Yanni K.-Y., Zhang, Alan H., Crawford, Theo, Zhu, Yifei, Fletcher, Nicholas L., Zhou, Zihan, Hamilton, Brett R., Stroet, Martin, Thurecht, Kristofer J., Mobli, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985607/
https://www.ncbi.nlm.nih.gov/pubmed/36871076
http://dx.doi.org/10.1038/s42004-023-00841-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985607/
https://www.ncbi.nlm.nih.gov/pubmed/36871076
http://dx.doi.org/10.1038/s42004-023-00841-5

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