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Fate of arsenicals in mice carrying the human AS3MT gene exposed to environmentally relevant levels of arsenite in drinking water

Although mice are widely used to study adverse effects of inorganic arsenic (iAs), higher rates of iAs methylation in mice than in humans may limit their utility as a model organism. A recently created 129S6 mouse strain in which the Borcs7/As3mt locus replaces the human BORCS7/AS3MT locus exhibits...

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Detalles Bibliográficos
Autores principales:	Douillet, Christelle, Miller, Madison, Cable, Peter H., Shi, Qing, El-Masri, Hisham, Matoušek, Tomáš, Koller, Beverly H., Thomas, David J., Stýblo, Miroslav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985638/ https://www.ncbi.nlm.nih.gov/pubmed/36871058 http://dx.doi.org/10.1038/s41598-023-30723-8

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