Selective androgen receptor modulation for muscle weakness in chronic obstructive pulmonary disease: a randomised control trial

BACKGROUND: Selective androgen receptor modulators (SARMs) increase muscle mass via the androgen receptor. This phase 2A trial investigated the effects of a SARM, GSK2881078, in conjunction with exercise, on leg strength in patients with chronic obstructive pulmonary disease (COPD) and impaired phys...

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Detalles Bibliográficos
Autores principales: Mohan, Divya, Rossiter, Harry, Watz, Henrik, Fogarty, Charles, Evans, Rachael A, Man, William, Tabberer, Maggie, Beerahee, Misba, Kumar, Subramanya, Millns, Helen, Thomas, Sebin, Tal-Singer, Ruth, Russell, Alan J, Holland, Marie Claire, Akinseye, Chika, Neil, David, Polkey, Michael I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Skeletal Muscle
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985744/
https://www.ncbi.nlm.nih.gov/pubmed/36283827
http://dx.doi.org/10.1136/thorax-2021-218360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985744/
https://www.ncbi.nlm.nih.gov/pubmed/36283827
http://dx.doi.org/10.1136/thorax-2021-218360

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