Cargando…

CCL17 exerts neuroprotection through activation of CCR4/mTORC2 axis in microglia after subarachnoid haemorrhage in rats

BACKGROUND AND PURPOSE: C-C motif chemokine ligand 17 (CCL17) presents an important role in immune regulation, which is critical in the pathophysiology of brain injury after subarachnoid haemorrhage (SAH). There is rare evidence to illustrate the function of CCL17 towards SAH. In this study, we try...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Anke, Liu, Yibo, Xu, Houshi, Zhang, Zeyu, Wang, Xiaoyu, Yuan, Ling, Lenahan, Cameron, Zhang, Chuan, Jiang, Junkun, Fang, Chaoyou, Fang, Yuanjian, Zhang, Jianmin, Chen, Sheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985806/ https://www.ncbi.nlm.nih.gov/pubmed/35882433 http://dx.doi.org/10.1136/svn-2022-001659

Ejemplares similares

Effect of stress‐induced hyperglycemia after non‐traumatic non‐aneurysmal subarachnoid hemorrhage on clinical complications and functional outcomes
por: Zhang, Zeyu, et al.
Publicado: (2022)

The Role of Caspase Family in Acute Brain Injury: The Potential Therapeutic Targets in the Future
por: Zhang, Anke, et al.
Publicado: (2022)

Inhibition of caspase-1-mediated inflammasome activation reduced blood coagulation in cerebrospinal fluid after subarachnoid haemorrhage
por: Fang, Yuanjian, et al.
Publicado: (2022)

Development of a nomogram for predicting clinical outcome in patients with angiogram‐negative subarachnoid hemorrhage
por: Zhang, Anke, et al.
Publicado: (2021)

New Mechanisms and Targets of Subarachnoid Hemorrhage: A Focus on Mitochondria
por: Zhang, Zeyu, et al.
Publicado: (2022)

Connection between oxidative stress and subcellular organelle in subarachnoid hemorrhage: Novel mechanisms and therapeutic implications
por: Zhang, Jiahao, et al.
Publicado: (2023)

Clinical Potential of Immunotherapies in Subarachnoid Hemorrhage Treatment: Mechanistic Dissection of Innate and Adaptive Immune Responses
por: Zhang, Anke, et al.
Publicado: (2023)

Validation and Comparison of Aneurysmal Subarachnoid Hemorrhage Grading Scales in Angiogram-Negative Subarachnoid Hemorrhage Patients
por: Fang, Yuanjian, et al.
Publicado: (2020)

The Role of Autophagy in Subarachnoid Hemorrhage: An Update
por: Fang, Yuanjian, et al.
Publicado: (2018)

Comparison of aneurysmal subarachnoid hemorrhage grading scores in patients with aneurysm clipping and coiling
por: Fang, Yuanjian, et al.
Publicado: (2020)

Pathogenic Role of mTORC1 and mTORC2 in Pulmonary Hypertension
por: Tang, Haiyang, et al.
Publicado: (2018)

The Updated Role of the Blood Brain Barrier in Subarachnoid Hemorrhage: From Basic and Clinical Studies
por: Chen, Sheng, et al.
Publicado: (2020)

The autophagy–lysosomal system in subarachnoid haemorrhage
por: Wu, Haijian, et al.
Publicado: (2016)

mTORC1 and mTORC2 in cancer and the tumor microenvironment
por: Kim, Laura C., et al.
Publicado: (2016)

Management of Spontaneous Subarachnoid Hemorrhage Patients with Negative Initial Digital Subtraction Angiogram Findings: Conservative or Aggressive?
por: Xu, Liang, et al.
Publicado: (2017)

Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2
por: Luo, Yan, et al.
Publicado: (2015)

TRP Family Genes Are Differently Expressed and Correlated with Immune Response in Glioma
por: Fang, Chaoyou, et al.
Publicado: (2022)

Natural Products for the Treatment of Post-stroke Depression
por: Fang, Chaoyou, et al.
Publicado: (2022)

New Insights of Early Brain Injury after Subarachnoid Hemorrhage: A Focus on the Caspase Family
por: Wang, Xiaoyu, et al.
Publicado: (2023)

Both mTORC1 and mTORC2 are involved in the regulation of cell adhesion
por: Chen, Long, et al.
Publicado: (2015)

The metabolic waste ammonium regulates mTORC2 and mTORC1 signaling
por: Merhi, Ahmad, et al.
Publicado: (2017)

SLC11A1 as a stratification indicator for immunotherapy or chemotherapy in patients with glioma
por: Xu, Houshi, et al.
Publicado: (2022)

Exosome Release Is Regulated by mTORC1
por: Zou, Wenchong, et al.
Publicado: (2018)

mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation
por: Ding, Xiaolei, et al.
Publicado: (2016)

LPS Induces mTORC1 and mTORC2 Activation During Monocyte Adhesion
por: Ribeiro, Marcelle C., et al.
Publicado: (2018)

mTORC1 and mTORC2 differentially promote natural killer cell development
por: Yang, Chao, et al.
Publicado: (2018)

mTORC1 and mTORC2 are differentially engaged in the development of laser-induced CNV
por: Yang, Jin Young, et al.
Publicado: (2019)

Dopamine neuron morphology and output are differentially controlled by mTORC1 and mTORC2
por: Kosillo, Polina, et al.
Publicado: (2022)

Cepharanthine Attenuates Early Brain Injury after Subarachnoid Hemorrhage in Mice via Inhibiting 15-Lipoxygenase-1-Mediated Microglia and Endothelial Cell Ferroptosis
por: Gao, Shiqi, et al.
Publicado: (2022)

SUBARACHNOID HÆMORRHAGE
Publicado: (1956)

Defects in mTORC1 Network and mTORC1-STAT3 Pathway Crosstalk Contributes to Non-inflammatory Hepatocellular Carcinoma
por: Li, Ting, et al.
Publicado: (2020)

CCL21-CCR7 signaling promotes microglia/macrophage recruitment and chemotherapy resistance in glioblastoma
por: Geraldo, Luiz Henrique, et al.
Publicado: (2023)

TLR4 counteracts BVRA signaling in human leukocytes via differential regulation of AMPK, mTORC1 and mTORC2
por: Zhang, Zhiyong, et al.
Publicado: (2019)

Regulation of Autophagy through TORC1 and mTORC1
por: Noda, Takeshi
Publicado: (2017)

Differential controls of MAIT cell effector polarization by mTORC1/mTORC2 via integrating cytokine and costimulatory signals
por: Tao, Huishan, et al.
Publicado: (2021)

Ferroptosis in glioma treatment: Current situation, prospects and drug applications
por: Zhou, Yuhang, et al.
Publicado: (2022)

Natural Compounds for SIRT1-Mediated Oxidative Stress and Neuroinflammation in Stroke: A Potential Therapeutic Target in the Future
por: Fang, Chaoyou, et al.
Publicado: (2022)

Novel role of STAT3 in microglia-dependent neuroinflammation after experimental subarachnoid haemorrhage
por: Zheng, Zhiyuan Vera, et al.
Publicado: (2021)

Regulation of mTORC1 by lysosomal calcium and calmodulin
por: Li, Ruo-Jing, et al.
Publicado: (2016)

Glutaminolysis feeds mTORC1
por: Durán, Raúl V., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_glq21jd6lqo26n26a578qcpa0p