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Maternal obesity and gestational diabetes reprogram the methylome of offspring beyond birth by inducing epigenetic signatures in metabolic and developmental pathways

BACKGROUND: Obesity is a negative chronic metabolic health condition that represents an additional risk for the development of multiple pathologies. Epidemiological studies have shown how maternal obesity or gestational diabetes mellitus during pregnancy constitute serious risk factors in relation t...

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Detalles Bibliográficos
Autores principales: Alba-Linares, Juan José, Pérez, Raúl F., Tejedor, Juan Ramón, Bastante-Rodríguez, David, Ponce, Francisco, Carbonell, Nuria García, Zafra, Rafael Gómez, Fernández, Agustín F., Fraga, Mario F., Lurbe, Empar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985842/
https://www.ncbi.nlm.nih.gov/pubmed/36870961
http://dx.doi.org/10.1186/s12933-023-01774-y