Functional inhibition of MEF2 by C/EBP is a possible mechanism of leukemia development by CEBP‐IGH fusion gene

CEBPA‐IGH, a fusion gene of the immunoglobulin heavy‐chain locus (IGH) and the CCAAT enhancer‐binding protein α (C/EBPα) gene, is recurrently found in B‐ALL cases and causes aberrant expression of C/EBPα, a master regulator of granulocyte differentiation, in B cells. Forced expression of C/EBPα in B...

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Detalles Bibliográficos
Autores principales: Odaira, Koya, Yasuda, Takahiko, Okada, Kentaro, Shimooka, Takuya, Kojima, Yukino, Noura, Mina, Tamura, Shogo, Kurahashi, Shingo, Iwamoto, Eisuke, Sanada, Masashi, Matsumura, Itaru, Miyazaki, Yasushi, Kojima, Tetsuhito, Kiyoi, Hitoshi, Tsuzuki, Shinobu, Hayakawa, Fumihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986073/
https://www.ncbi.nlm.nih.gov/pubmed/36341510
http://dx.doi.org/10.1111/cas.15641

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