Cargando…

LPLUNC1 reduces glycolysis in nasopharyngeal carcinoma cells through the PHB1‐p53/c‐Myc axis

Cancer cells prefer glycolysis to support their proliferation. Our previous studies have shown that the long palate, lung, and nasal epithelial cell clone 1 (LPLUNC1) can upregulate prohibitin 1 (PHB1) expression to inhibit the proliferation of nasopharyngeal carcinoma (NPC) cells. Given that PHB1 i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Oyang, Linda, Ouyang, Lei, Yang, Lixia, Lin, Jinguan, Xia, Longzheng, Tan, Shiming, Wu, Nayiyuan, Han, Yaqian, Yang, Yiqing, Li, Jian, Chen, Xiaohui, Tang, Yanyan, Su, Min, Luo, Xia, Li, Jinyun, Xiong, Wei, Zeng, Zhaoyang, Liao, Qianjin, Zhou, Yujuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986081/ https://www.ncbi.nlm.nih.gov/pubmed/36382614 http://dx.doi.org/10.1111/cas.15662

Ejemplares similares

LPLUNC1 stabilises PHB1 by counteracting TRIM21-mediated ubiquitination to inhibit NF-κB activity in nasopharyngeal carcinoma
por: Wang, Heran, et al.
Publicado: (2019)

The function of prohibitins in mitochondria and the clinical potentials
por: Oyang, Linda, et al.
Publicado: (2022)

The POU2F1-ALDOA axis promotes the proliferation and chemoresistance of colon cancer cells by enhancing glycolysis and the pentose phosphate pathway activity
por: Lin, Jinguan, et al.
Publicado: (2022)

Metabolic reprogramming and epigenetic modifications in cancer: from the impacts and mechanisms to the treatment potential
por: Xu, Xuemeng, et al.
Publicado: (2023)

Exosomal miR-205-5p enhances angiogenesis and nasopharyngeal carcinoma metastasis by targeting desmocollin-2
por: Yang, Wenjuan, et al.
Publicado: (2022)

Rac1 promotes the reprogramming of glucose metabolism and the growth of colon cancer cells through upregulating SOX9
por: Liang, Jiaxin, et al.
Publicado: (2022)

HYOU1, Regulated by LPLUNC1, Is Up-Regulated in Nasopharyngeal Carcinoma and Associated with Poor Prognosis
por: Zhou, Yujuan, et al.
Publicado: (2016)

Clinical significance and integrative analysis of the cuproptosis-associated genes in head and neck squamous cell carcinoma
por: Peng, Qiu, et al.
Publicado: (2023)

MiRNAs in Radiotherapy Resistance of Nasopharyngeal Carcinoma
por: Tian, Yutong, et al.
Publicado: (2020)

The cancer metabolic reprogramming and immune response
por: Xia, Longzheng, et al.
Publicado: (2021)

The role of tripartite motif-containing 28 in cancer progression and its therapeutic potentials
por: Yang, Yiqing, et al.
Publicado: (2023)

Organoids: opportunities and challenges of cancer therapy
por: Jiang, Xianjie, et al.
Publicado: (2023)

Exosomes in Nasopharyngeal Carcinoma
por: Zhou, Yujuan, et al.
Publicado: (2018)

BPIFB1 (LPLUNC1) inhibits radioresistance in nasopharyngeal carcinoma by inhibiting VTN expression
por: Wei, Fang, et al.
Publicado: (2018)

Rac1, A Potential Target for Tumor Therapy
por: Liang, Jiaxin, et al.
Publicado: (2021)

The roles of long non-coding RNAs in lung cancer
por: Cao, Zhe, et al.
Publicado: (2022)

BPIFB1 (LPLUNC1) inhibits migration and invasion of nasopharyngeal carcinoma by interacting with VTN and VIM
por: Wei, Fang, et al.
Publicado: (2018)

Exosomal cargos-mediated metabolic reprogramming in tumor microenvironment
por: Tan, Shiming, et al.
Publicado: (2023)

Biological Function of HYOU1 in Tumors and Other Diseases
por: Rao, Shan, et al.
Publicado: (2021)

Phase separation in Cancer: From the Impacts and Mechanisms to Treatment potentials
por: Peng, Qiu, et al.
Publicado: (2022)

Exosomal miRNAs in tumor microenvironment
por: Tan, Shiming, et al.
Publicado: (2020)

The roles of glucose metabolic reprogramming in chemo- and radio-resistance
por: Lin, Jinguan, et al.
Publicado: (2019)

RAC1 Involves in the Radioresistance by Mediating Epithelial-Mesenchymal Transition in Lung Cancer
por: Tan, Shiming, et al.
Publicado: (2020)

Corrigendum: RAC1 Involves in the Radioresistance by Mediating Epithelial-Mesenchymal Transition in Lung Cancer
por: Tan, Shiming, et al.
Publicado: (2020)

The functions and mechanisms of prefoldin complex and prefoldin-subunits
por: Liang, Jiaxin, et al.
Publicado: (2020)

LPLUNC1 Inhibits Nasopharyngeal Carcinoma Cell Growth via Down-Regulation of the MAP Kinase and Cyclin D1/E2F Pathways
por: Yang, Yixin, et al.
Publicado: (2013)

Correction: LPLUNC1 Inhibits Nasopharyngeal Carcinoma Cell Growth via Down-Regulation of the MAP Kinase and Cyclin D1/E2F Pathways
por: Yang, Yixin, et al.
Publicado: (2013)

Overexpression of PAK1 Correlates with Aberrant Expression of EMT Markers and Poor Prognosis in Non-Small Cell Lung Cancer
por: Yang, Zhiying, et al.
Publicado: (2017)

Cancer stem cells in progression of colorectal cancer
por: Zhou, Yujuan, et al.
Publicado: (2017)

Role of the NFκB-signaling pathway in cancer
por: Xia, Longzheng, et al.
Publicado: (2018)

Rac1 overexpression is correlated with epithelial mesenchymal transition and predicts poor prognosis in non-small cell lung cancer
por: Zhou, Yujuan, et al.
Publicado: (2016)

Diallyl disulfide inhibits colon cancer metastasis by suppressing Rac1-mediated epithelial-mesenchymal transition
por: Xia, Longzheng, et al.
Publicado: (2019)

BPIFB1 (LPLUNC1) is upregulated in cystic fibrosis lung disease
por: Bingle, Lynne, et al.
Publicado: (2012)

Impacts and mechanisms of alternative mRNA splicing in cancer metabolism, immune response, and therapeutics
por: Peng, Qiu, et al.
Publicado: (2022)

High expression of calreticulin indicates poor prognosis and modulates cell migration and invasion via activating Stat3 in nasopharyngeal carcinoma
por: Han, Yaqian, et al.
Publicado: (2019)

Differential localisation of BPIFA1 (SPLUNC1) and BPIFB1 (LPLUNC1) in the nasal and oral cavities of mice
por: Musa, Maslinda, et al.
Publicado: (2012)

TRPM7 silencing modulates glucose metabolic reprogramming to inhibit the growth of ovarian cancer by enhancing AMPK activation to promote HIF-1α degradation
por: Chen, Yongchang, et al.
Publicado: (2022)

Human LPLUNC1 is a secreted product of goblet cells and minor glands of the respiratory and upper aerodigestive tracts
por: Bingle, Colin D., et al.
Publicado: (2010)

Targeting MYC-enhanced glycolysis for the treatment of small cell lung cancer
por: Cargill, Kasey R., et al.
Publicado: (2021)

FOXM1 regulates glycolysis in nasopharyngeal carcinoma cells through PDK1
por: Yang, Qing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ql2o18ov1u15vulpog0vhvj0fk