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Targeting PYCR2 inhibits intraperitoneal metastatic tumors of mouse colorectal cancer in a proline‐independent approach

Whether proline deficiency is a metabolic vulnerability in colorectal tumors is unknown. The aim of this study was to investigate the effects of proline metabolism‐related genes and exogenous proline on the progression of colorectal cancer (CRC). We aimed to further clarify the role of pyrroline‐5‐c...

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Detalles Bibliográficos
Autores principales:	Zhang, Qi, Luo, Hai, Xun, Jing, Ma, Yuan, Yang, Lei, Zhang, Lanqiu, Wang, Ximo, Yu, Xiangyang, Wang, Botao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	ORIGINAL ARTICLES
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986086/ https://www.ncbi.nlm.nih.gov/pubmed/36308281 http://dx.doi.org/10.1111/cas.15635

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