Shikonin reverses pyruvate kinase isoform M2‐mediated propranolol resistance in infantile hemangioma through reactive oxygen species‐induced autophagic dysfunction

Infantile hemangioma (IH) is the most common benign tumor in infancy. Propranolol, a nonselective β‐adrenergic receptor blocker, is now the first‐line therapy for IH. Recently, low sensitivity to propranolol therapy has become one major reason for the failure of IH treatment. However, the exact unde...

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Detalles Bibliográficos
Autores principales: Yang, Enli, Wang, Xuan, Huang, Shengyun, Li, Mingyang, Li, Yiming, Geng, Yiming, Liu, Xuejian, Chen, Zhanwei, Zhang, Dongsheng, Wu, Haiwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986094/
https://www.ncbi.nlm.nih.gov/pubmed/36369903
http://dx.doi.org/10.1111/cas.15649

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