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Long-term impact of primary prophylaxis on joint status in patients with severe hemophilia A
BACKGROUND: Primary prophylaxis with factor VIII concentrates is the therapeutic gold standard for severe hemophilia A. Although this approach will change substantially with the use of nonsubstitutive therapies, the long-term effects of primary prophylaxis remain unclear. We present information on j...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986103/ https://www.ncbi.nlm.nih.gov/pubmed/36891521 http://dx.doi.org/10.1016/j.rpth.2022.100005 |