Design of a stabilized RBD enables potently neutralizing SARS-CoV-2 single-component nanoparticle vaccines

Waning immunity and emerging variants necessitate continued vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Improvements in vaccine safety, tolerability, and ease of manufacturing would benefit these efforts. Here, we develop a potent and easily manufactured nanopar...

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Detalles Bibliográficos
Autores principales: Dickey, Thayne H., Ma, Rui, Orr-Gonzalez, Sachy, Ouahes, Tarik, Patel, Palak, McAleese, Holly, Butler, Brandi, Eudy, Elizabeth, Eaton, Brett, Murphy, Michael, Kwan, Jennifer L., Salinas, Nichole D., Holbrook, Michael R., Lambert, Lynn E., Tolia, Niraj H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986124/
https://www.ncbi.nlm.nih.gov/pubmed/36943870
http://dx.doi.org/10.1016/j.celrep.2023.112266

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986124/
https://www.ncbi.nlm.nih.gov/pubmed/36943870
http://dx.doi.org/10.1016/j.celrep.2023.112266

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