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Prostaglandin E(2) mediates the late phase of ischemic preconditioning in the heart via its receptor subtype EP(4)

Ischemic preconditioning (IPC) describes a phenomenon wherein brief ischemia of the heart induces a potent cardioprotective mechanism against succeeding ischemic insult. Cyclooxygenase-2 (COX-2), a rate-limiting enzyme in prostanoid biosynthesis, is upregulated in the ischemic heart and contributes...

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Detalles Bibliográficos
Autores principales:	Kanno, Takayasu, Nakagawa, Naoki, Aonuma, Tatsuya, Kawabe, Jun-ichi, Yuhki, Koh-ichi, Takehara, Naofumi, Hasebe, Naoyuki, Ushikubi, Fumitaka
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Japan 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986202/ https://www.ncbi.nlm.nih.gov/pubmed/36522555 http://dx.doi.org/10.1007/s00380-022-02219-4

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