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TUBB2B facilitates progression of hepatocellular carcinoma by regulating cholesterol metabolism through targeting HNF4A/CYP27A1

Cholesterol metabolism plays a critical role in the progression of hepatocellular carcinoma (HCC), but it is not clear how cholesterol metabolism is regulated. The tubulin beta class I genes (TUBBs) are associated with the prognosis of many different cancers. To confirm the function of TUBBs in HCC,...

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Detalles Bibliográficos
Autores principales: Wang, Xiaobo, Shi, Jiawei, Huang, Mingming, Chen, Jiehong, Dan, Jia, Tang, Yunhua, Guo, Zhiyong, He, Xiaoshun, Zhao, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986231/
https://www.ncbi.nlm.nih.gov/pubmed/36872411
http://dx.doi.org/10.1038/s41419-023-05687-2