Cargando…
Should aspirin be replaced with ADP blockers and anti-GPVI to manage thrombosis?
Platelets have a pivotal role in maintaining cardiovascular homeostasis. They are kept docile by endothelial-derived mediators. Aberration in haemostatic balance predisposes an individual to an elevated risk of a prothrombotic environment. Anti-platelet therapy has been a key component to reduce thi...
Autores principales: | Khan, Hafsa, Ghulam, Tahira, Ahmed, Naseer, Rafai Babar, Muhammad, Calaminus, Simon DJ, Zuhair Yusuf, Muhammad |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986383/ https://www.ncbi.nlm.nih.gov/pubmed/37931411 http://dx.doi.org/10.1530/VB-22-0010 |
Ejemplares similares
-
Luteolin inhibits GPVI-mediated platelet activation, oxidative stress, and thrombosis
por: Ye, Yujia, et al.
Publicado: (2023) -
Characterization of GPVI- or GPVI-CD39-Coated Nanoparticles and Their Impact on In Vitro Thrombus Formation
por: Nestele, Jeremy A., et al.
Publicado: (2021) -
Anti‐GPVI nanobody blocks collagen‐ and atherosclerotic plaque–induced GPVI clustering, signaling, and thrombus formation
por: Jooss, Natalie J., et al.
Publicado: (2022) -
Comparison of the GPVI inhibitors losartan and honokiol
por: Onselaer, Marie-Blanche, et al.
Publicado: (2019) -
Clustering of glycoprotein VI (GPVI) dimers upon adhesion to collagen as a mechanism to regulate GPVI signaling in platelets
por: Poulter, N. S., et al.
Publicado: (2017)