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p53 mutation and deletion contribute to tumor immune evasion

TP53 (or p53) is widely accepted to be a tumor suppressor. Upon various cellular stresses, p53 mediates cell cycle arrest and apoptosis to maintain genomic stability. p53 is also discovered to suppress tumor growth through regulating metabolism and ferroptosis. However, p53 is always lost or mutated...

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Detalles Bibliográficos
Autores principales:	Liu, Siyang, Liu, Tianyao, Jiang, Jiaxuan, Guo, Hongqian, Yang, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986462/ https://www.ncbi.nlm.nih.gov/pubmed/36891151 http://dx.doi.org/10.3389/fgene.2023.1088455

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