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Voltage sensor dynamics of a bacterial voltage-gated sodium channel NavAb reveal three conformational states

High-resolution structures of voltage-gated sodium channels (Nav) were first obtained from a prokaryotic ortholog NavAb, which provided important mechanistic insights into Na(+) selectivity and voltage gating. Unlike eukaryotic Navs, the NavAb channel is formed by four identical subunits, but its io...

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Detalles Bibliográficos
Autores principales:	Han, Shuo, Vance, Joshua, Jones, Samuel, DeCata, Jenna, Tran, Kimberly, Cummings, John, Wang, Shizhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986516/ https://www.ncbi.nlm.nih.gov/pubmed/36736429 http://dx.doi.org/10.1016/j.jbc.2023.102967

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