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A-910823, a squalene-based emulsion adjuvant, induces T follicular helper cells and humoral immune responses via α-tocopherol component
BACKGROUND: Adjuvants are chemical or biological materials that enhance the efficacy of vaccines. A-910823 is a squalene-based emulsion adjuvant used for S-268019-b, a novel vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is currently in clinical development. Publis...
Autores principales: | Yoshioka, Yuya, Kobiyama, Kouji, Hayashi, Tomoya, Onishi, Motoyasu, Yanagida, Yosuke, Nakagawa, Takayuki, Hashimoto, Masayuki, Nishinaka, Anri, Hirose, Jun, Asaoka, Yoshiji, Tajiri, Minako, Hayata, Atsushi, Ishida, Satoru, Omoto, Shinya, Nagira, Morio, Ishii, Ken J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986537/ https://www.ncbi.nlm.nih.gov/pubmed/36891311 http://dx.doi.org/10.3389/fimmu.2023.1116238 |
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