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Human brain organoid model of maternal immune activation identifies radial glia cells as selectively vulnerable

Maternal immune activation (MIA) during critical windows of gestation is correlated with long-term neurodevelopmental deficits in the offspring, including increased risk for autism spectrum disorder (ASD) in humans. Interleukin 6 (IL-6) derived from the gestational parent is one of the major molecul...

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Detalles Bibliográficos
Autores principales: Sarieva, Kseniia, Kagermeier, Theresa, Khakipoor, Shokoufeh, Atay, Ezgi, Yentür, Zeynep, Becker, Katharina, Mayer, Simone
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986664/
https://www.ncbi.nlm.nih.gov/pubmed/36878967
http://dx.doi.org/10.1038/s41380-023-01997-1

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