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Human brain organoid model of maternal immune activation identifies radial glia cells as selectively vulnerable
Maternal immune activation (MIA) during critical windows of gestation is correlated with long-term neurodevelopmental deficits in the offspring, including increased risk for autism spectrum disorder (ASD) in humans. Interleukin 6 (IL-6) derived from the gestational parent is one of the major molecul...
Autores principales: | Sarieva, Kseniia, Kagermeier, Theresa, Khakipoor, Shokoufeh, Atay, Ezgi, Yentür, Zeynep, Becker, Katharina, Mayer, Simone |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986664/ https://www.ncbi.nlm.nih.gov/pubmed/36878967 http://dx.doi.org/10.1038/s41380-023-01997-1 |
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