Cargando…
Linguistic and Psychometric Validation of the Cognition Bolt-On Version of the Japanese EQ-5D-5L for the Elderly
BACKGROUND: The need for a cognition bolt-on version of the EQ-5D, which would capture cognitive impairment by adding a dimension to the generic instrument assessing health status, has been increasing in Japan. OBJECTIVE: To develop a cognition bolt-on version of the 5-level EQ-5D (EQ-5D-5L+C), we l...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
IOS Press
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986695/ https://www.ncbi.nlm.nih.gov/pubmed/36641680 http://dx.doi.org/10.3233/JAD-221080 |
_version_ | 1784901225915875328 |
---|---|
author | Igarashi, Ataru Sakata, Yukinori Azuma-Kasai, Mie Kamiyama, Harue Kawaguchi, Mika Tomita, Kiyoyuki Ishii, Mika Ikeda, Manabu |
author_facet | Igarashi, Ataru Sakata, Yukinori Azuma-Kasai, Mie Kamiyama, Harue Kawaguchi, Mika Tomita, Kiyoyuki Ishii, Mika Ikeda, Manabu |
author_sort | Igarashi, Ataru |
collection | PubMed |
description | BACKGROUND: The need for a cognition bolt-on version of the EQ-5D, which would capture cognitive impairment by adding a dimension to the generic instrument assessing health status, has been increasing in Japan. OBJECTIVE: To develop a cognition bolt-on version of the 5-level EQ-5D (EQ-5D-5L+C), we linguistically validated a cognition dimension and psychometrically validated the EQ-5D-5L+C. METHODS: Following linguistic validation of the cognition dimension, psychometric validation of the EQ-5D-5L+C proxy version utilized anonymized data collected from nursing home residents between October 2021 to April 2022. The validity, reliability, and sensitivity to change were evaluated. RESULTS: Data from 254 participants, including the finalized Japanese EQ-5D-5L+C proxy version, were analyzed for the psychometric validation. Mean (±standard deviation) age and Mini-Mental State Examination (MMSE) scores were 87.14±7.29 years and 15.76±8.46, respectively. The correlation was strongest between the cognition dimension and MMSE scores (r(s) = –0.640). Test-retest reliability was good in the cognition dimension in both baseline and two-time points (3 months: k = 0.644; 6 months: k = 0.656). Although a correlation between changes in the cognition dimension and those in the MMSE score from baseline was weak (3 months: r(s) = –0.191; 6 months: r(s) = –0.267), a correlation with changes in the MMSE score was higher when the cognition dimension was added compared to the EQ-5D alone (3 months: r(s) = –0.142 versus r(s) = –0.074). CONCLUSION: The Japanese EQ-5D-5L+C proxy version developed is a valid tool that captures health status including cognitive function, with a consideration for an over-time assessment. The benefits in adding the cognition dimension to the EQ-5D-5L to assess health state were suggested. |
format | Online Article Text |
id | pubmed-9986695 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | IOS Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-99866952023-03-07 Linguistic and Psychometric Validation of the Cognition Bolt-On Version of the Japanese EQ-5D-5L for the Elderly Igarashi, Ataru Sakata, Yukinori Azuma-Kasai, Mie Kamiyama, Harue Kawaguchi, Mika Tomita, Kiyoyuki Ishii, Mika Ikeda, Manabu J Alzheimers Dis Research Article BACKGROUND: The need for a cognition bolt-on version of the EQ-5D, which would capture cognitive impairment by adding a dimension to the generic instrument assessing health status, has been increasing in Japan. OBJECTIVE: To develop a cognition bolt-on version of the 5-level EQ-5D (EQ-5D-5L+C), we linguistically validated a cognition dimension and psychometrically validated the EQ-5D-5L+C. METHODS: Following linguistic validation of the cognition dimension, psychometric validation of the EQ-5D-5L+C proxy version utilized anonymized data collected from nursing home residents between October 2021 to April 2022. The validity, reliability, and sensitivity to change were evaluated. RESULTS: Data from 254 participants, including the finalized Japanese EQ-5D-5L+C proxy version, were analyzed for the psychometric validation. Mean (±standard deviation) age and Mini-Mental State Examination (MMSE) scores were 87.14±7.29 years and 15.76±8.46, respectively. The correlation was strongest between the cognition dimension and MMSE scores (r(s) = –0.640). Test-retest reliability was good in the cognition dimension in both baseline and two-time points (3 months: k = 0.644; 6 months: k = 0.656). Although a correlation between changes in the cognition dimension and those in the MMSE score from baseline was weak (3 months: r(s) = –0.191; 6 months: r(s) = –0.267), a correlation with changes in the MMSE score was higher when the cognition dimension was added compared to the EQ-5D alone (3 months: r(s) = –0.142 versus r(s) = –0.074). CONCLUSION: The Japanese EQ-5D-5L+C proxy version developed is a valid tool that captures health status including cognitive function, with a consideration for an over-time assessment. The benefits in adding the cognition dimension to the EQ-5D-5L to assess health state were suggested. IOS Press 2023-02-14 /pmc/articles/PMC9986695/ /pubmed/36641680 http://dx.doi.org/10.3233/JAD-221080 Text en © 2023 – The authors. Published by IOS Press https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) License (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Research Article Igarashi, Ataru Sakata, Yukinori Azuma-Kasai, Mie Kamiyama, Harue Kawaguchi, Mika Tomita, Kiyoyuki Ishii, Mika Ikeda, Manabu Linguistic and Psychometric Validation of the Cognition Bolt-On Version of the Japanese EQ-5D-5L for the Elderly |
title | Linguistic and Psychometric Validation of the Cognition Bolt-On Version of the Japanese EQ-5D-5L for the Elderly |
title_full | Linguistic and Psychometric Validation of the Cognition Bolt-On Version of the Japanese EQ-5D-5L for the Elderly |
title_fullStr | Linguistic and Psychometric Validation of the Cognition Bolt-On Version of the Japanese EQ-5D-5L for the Elderly |
title_full_unstemmed | Linguistic and Psychometric Validation of the Cognition Bolt-On Version of the Japanese EQ-5D-5L for the Elderly |
title_short | Linguistic and Psychometric Validation of the Cognition Bolt-On Version of the Japanese EQ-5D-5L for the Elderly |
title_sort | linguistic and psychometric validation of the cognition bolt-on version of the japanese eq-5d-5l for the elderly |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986695/ https://www.ncbi.nlm.nih.gov/pubmed/36641680 http://dx.doi.org/10.3233/JAD-221080 |
work_keys_str_mv | AT igarashiataru linguisticandpsychometricvalidationofthecognitionboltonversionofthejapaneseeq5d5lfortheelderly AT sakatayukinori linguisticandpsychometricvalidationofthecognitionboltonversionofthejapaneseeq5d5lfortheelderly AT azumakasaimie linguisticandpsychometricvalidationofthecognitionboltonversionofthejapaneseeq5d5lfortheelderly AT kamiyamaharue linguisticandpsychometricvalidationofthecognitionboltonversionofthejapaneseeq5d5lfortheelderly AT kawaguchimika linguisticandpsychometricvalidationofthecognitionboltonversionofthejapaneseeq5d5lfortheelderly AT tomitakiyoyuki linguisticandpsychometricvalidationofthecognitionboltonversionofthejapaneseeq5d5lfortheelderly AT ishiimika linguisticandpsychometricvalidationofthecognitionboltonversionofthejapaneseeq5d5lfortheelderly AT ikedamanabu linguisticandpsychometricvalidationofthecognitionboltonversionofthejapaneseeq5d5lfortheelderly |