An evolutionary molecular adaptation of an unusual stefin from the liver fluke Fasciola hepatica redefines the cystatin superfamily

Fasciolosis is a worldwide parasitic disease of ruminants and an emerging human disease caused by the liver fluke Fasciola hepatica. The cystatin superfamily of cysteine protease inhibitors is composed of distinct families of intracellular stefins and secreted true cystatins. FhCyLS-2 from F. hepati...

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Detalles Bibliográficos
Autores principales: Buša, Michal, Matoušková, Zuzana, Bartošová-Sojková, Pavla, Pachl, Petr, Řezáčová, Pavlína, Eichenberger, Ramon Marc, Deplazes, Peter, Horn, Martin, Štefanić, Saša, Mareš, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Research Article Collection: Protein Structure and Folding
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986714/
https://www.ncbi.nlm.nih.gov/pubmed/36736427
http://dx.doi.org/10.1016/j.jbc.2023.102970

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