Clinical profile of patients with cardiac amyloidosis in India

Limited data exists on patients with cardiac amyloidosis (CA) in India, due to underdiagnosis and late presentation. We present single centre data from 13 patients over a 4 year period with a median age of 65 years. A majority presented with symptomatic heart failure (69%) and eight patients had con...

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Detalles Bibliográficos
Autores principales: Mohan, Bishav, Singh, Suvir, Tandon, Rohit, Batta, Akash, Singal, Gautam, Singh, Gurbhej, Singh, Bhupinder, Goyal, Abhishek, Chhabra, Shibba Takkar, Naved, Khizar, Jain, Aayush, Wander, Gurpreet S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986727/
https://www.ncbi.nlm.nih.gov/pubmed/36572145
http://dx.doi.org/10.1016/j.ihj.2022.12.006
Descripción
Sumario:Limited data exists on patients with cardiac amyloidosis (CA) in India, due to underdiagnosis and late presentation. We present single centre data from 13 patients over a 4 year period with a median age of 65 years. A majority presented with symptomatic heart failure (69%) and eight patients had confirmed AL amyloidosis. At the end of the follow up period, 46% patients died, with 30% of the overall cohort dead within six months. Among the survivors, 71% continue to have NYHA grade III/IV symptoms. A suggested algorithm for earlier diagnosis in resource constrained settings is also presented.

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