Clinical profile of patients with cardiac amyloidosis in India

Limited data exists on patients with cardiac amyloidosis (CA) in India, due to underdiagnosis and late presentation. We present single centre data from 13 patients over a 4 year period with a median age of 65 years. A majority presented with symptomatic heart failure (69%) and eight patients had con...

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Autores principales: Mohan, Bishav, Singh, Suvir, Tandon, Rohit, Batta, Akash, Singal, Gautam, Singh, Gurbhej, Singh, Bhupinder, Goyal, Abhishek, Chhabra, Shibba Takkar, Naved, Khizar, Jain, Aayush, Wander, Gurpreet S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Brief
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986727/
https://www.ncbi.nlm.nih.gov/pubmed/36572145
http://dx.doi.org/10.1016/j.ihj.2022.12.006
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author Mohan, Bishav
Singh, Suvir
Tandon, Rohit
Batta, Akash
Singal, Gautam
Singh, Gurbhej
Singh, Bhupinder
Goyal, Abhishek
Chhabra, Shibba Takkar
Naved, Khizar
Jain, Aayush
Wander, Gurpreet S.
author_facet Mohan, Bishav
Singh, Suvir
Tandon, Rohit
Batta, Akash
Singal, Gautam
Singh, Gurbhej
Singh, Bhupinder
Goyal, Abhishek
Chhabra, Shibba Takkar
Naved, Khizar
Jain, Aayush
Wander, Gurpreet S.
author_sort Mohan, Bishav
collection PubMed
description Limited data exists on patients with cardiac amyloidosis (CA) in India, due to underdiagnosis and late presentation. We present single centre data from 13 patients over a 4 year period with a median age of 65 years. A majority presented with symptomatic heart failure (69%) and eight patients had confirmed AL amyloidosis. At the end of the follow up period, 46% patients died, with 30% of the overall cohort dead within six months. Among the survivors, 71% continue to have NYHA grade III/IV symptoms. A suggested algorithm for earlier diagnosis in resource constrained settings is also presented.
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spelling pubmed-99867272023-03-07 Clinical profile of patients with cardiac amyloidosis in India Mohan, Bishav Singh, Suvir Tandon, Rohit Batta, Akash Singal, Gautam Singh, Gurbhej Singh, Bhupinder Goyal, Abhishek Chhabra, Shibba Takkar Naved, Khizar Jain, Aayush Wander, Gurpreet S. Indian Heart J Research Brief Limited data exists on patients with cardiac amyloidosis (CA) in India, due to underdiagnosis and late presentation. We present single centre data from 13 patients over a 4 year period with a median age of 65 years. A majority presented with symptomatic heart failure (69%) and eight patients had confirmed AL amyloidosis. At the end of the follow up period, 46% patients died, with 30% of the overall cohort dead within six months. Among the survivors, 71% continue to have NYHA grade III/IV symptoms. A suggested algorithm for earlier diagnosis in resource constrained settings is also presented. Elsevier 2023 2022-12-23 /pmc/articles/PMC9986727/ /pubmed/36572145 http://dx.doi.org/10.1016/j.ihj.2022.12.006 Text en © 2022 Cardiological Society of India. Published by Elsevier, a division of RELX India, Pvt. Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Research Brief
Mohan, Bishav
Singh, Suvir
Tandon, Rohit
Batta, Akash
Singal, Gautam
Singh, Gurbhej
Singh, Bhupinder
Goyal, Abhishek
Chhabra, Shibba Takkar
Naved, Khizar
Jain, Aayush
Wander, Gurpreet S.
Clinical profile of patients with cardiac amyloidosis in India
title Clinical profile of patients with cardiac amyloidosis in India
title_full Clinical profile of patients with cardiac amyloidosis in India
title_fullStr Clinical profile of patients with cardiac amyloidosis in India
title_full_unstemmed Clinical profile of patients with cardiac amyloidosis in India
title_short Clinical profile of patients with cardiac amyloidosis in India
title_sort clinical profile of patients with cardiac amyloidosis in india
topic Research Brief
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986727/
https://www.ncbi.nlm.nih.gov/pubmed/36572145
http://dx.doi.org/10.1016/j.ihj.2022.12.006
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