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20 years of crystal hits: progress and promise in ultrahigh-throughput crystallization screening
Diffraction-based structural methods contribute a large fraction of the biomolecular structural models available, providing a critical understanding of macromolecular architecture. These methods require crystallization of the target molecule, which remains a primary bottleneck in crystal-based struc...
Autores principales: | Lynch, Miranda L., Snell, M. Elizabeth, Potter, Stephen A., Snell, Edward H., Bowman, Sarah E. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986797/ https://www.ncbi.nlm.nih.gov/pubmed/36876429 http://dx.doi.org/10.1107/S2059798323001274 |
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