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Severity Assessment in Rats Undergoing Subarachnoid Hemorrhage Induction by Endovascular Perforation or Corresponding Sham Surgery

INTRODUCTION: Animal models for preclinical research of subarachnoid hemorrhage (SAH) are widely used as much of the pathophysiology remains unknown. However, the burden of these models inflicted on the animals is not well characterized. The European directive requires severity assessment-based allo...

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Detalles Bibliográficos
Autores principales: Bach-Hagemann, Annika, Harder, Ekaterina, Warner, Laura, Conzen-Dilger, Catharina, Schmidt, Tobias Philip, Pinkernell, Sarah, Palme, Rupert, Lindauer, Ute
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986840/
http://dx.doi.org/10.1159/000524432