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Severity Assessment in Rats Undergoing Subarachnoid Hemorrhage Induction by Endovascular Perforation or Corresponding Sham Surgery
INTRODUCTION: Animal models for preclinical research of subarachnoid hemorrhage (SAH) are widely used as much of the pathophysiology remains unknown. However, the burden of these models inflicted on the animals is not well characterized. The European directive requires severity assessment-based allo...
Autores principales: | Bach-Hagemann, Annika, Harder, Ekaterina, Warner, Laura, Conzen-Dilger, Catharina, Schmidt, Tobias Philip, Pinkernell, Sarah, Palme, Rupert, Lindauer, Ute |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986840/ http://dx.doi.org/10.1159/000524432 |
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