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Effect of serum albumin level on high-dose methotrexate induced toxicities in acute lymphoblastic leukemia patients

OBJECTIVES: Methotrexate (MTX) is a key therapeutic agent for leukemias. When given in high doses, leucovorin rescue is added to reduce its toxicity. It has been postulated that low albumin levels are associated with delayed clearance and increased toxicity of MTX. Hence, this prospective cohort stu...

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Detalles Bibliográficos
Autores principales: Mirza, Mehdi Ali, D. Aruna, Konatam, Meher Lakshmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Qassim Uninversity 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986883/
https://www.ncbi.nlm.nih.gov/pubmed/36891042