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Mathematical model and stability analysis on the transmission dynamics of skin sores

In this study, a non-linear deterministic model for the transmission dynamics of skin sores (impetigo) disease is developed and analysed by the help of stability of differential equations. Some basic properties of the model including existence and positivity as well as boundedness of the solutions o...

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Autores principales: Fantaye, Abayneh Kebede, Goshu, Masitawal Demsie, Zeleke, Berhanu Belay, Gessesse, Adane Abebaw, Endalew, Mehari Fentahun, Birhanu, Zerihun Kinfe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987028/
https://www.ncbi.nlm.nih.gov/pubmed/36397272
http://dx.doi.org/10.1017/S0950268822001807
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author Fantaye, Abayneh Kebede
Goshu, Masitawal Demsie
Zeleke, Berhanu Belay
Gessesse, Adane Abebaw
Endalew, Mehari Fentahun
Birhanu, Zerihun Kinfe
author_facet Fantaye, Abayneh Kebede
Goshu, Masitawal Demsie
Zeleke, Berhanu Belay
Gessesse, Adane Abebaw
Endalew, Mehari Fentahun
Birhanu, Zerihun Kinfe
author_sort Fantaye, Abayneh Kebede
collection PubMed
description In this study, a non-linear deterministic model for the transmission dynamics of skin sores (impetigo) disease is developed and analysed by the help of stability of differential equations. Some basic properties of the model including existence and positivity as well as boundedness of the solutions of the model are investigated. The disease-free and endemic equilibrium were investigated, as well as the basic reproduction number, R(0), also calculated using the next-generation matrix approach. When R(0) < 1, the model's stability analysis reveals that the system is asymptotically stable at disease-free critical point globally as well as locally. If R(0) > 1, the system is asymptotically stable at disease-endemic equilibrium both locally and globally. The long-term behaviour of the skin sores model's steady-state solution in a population is investigated using numerical simulations of the model.
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spelling pubmed-99870282023-03-07 Mathematical model and stability analysis on the transmission dynamics of skin sores Fantaye, Abayneh Kebede Goshu, Masitawal Demsie Zeleke, Berhanu Belay Gessesse, Adane Abebaw Endalew, Mehari Fentahun Birhanu, Zerihun Kinfe Epidemiol Infect Original Paper In this study, a non-linear deterministic model for the transmission dynamics of skin sores (impetigo) disease is developed and analysed by the help of stability of differential equations. Some basic properties of the model including existence and positivity as well as boundedness of the solutions of the model are investigated. The disease-free and endemic equilibrium were investigated, as well as the basic reproduction number, R(0), also calculated using the next-generation matrix approach. When R(0) < 1, the model's stability analysis reveals that the system is asymptotically stable at disease-free critical point globally as well as locally. If R(0) > 1, the system is asymptotically stable at disease-endemic equilibrium both locally and globally. The long-term behaviour of the skin sores model's steady-state solution in a population is investigated using numerical simulations of the model. Cambridge University Press 2022-11-18 /pmc/articles/PMC9987028/ /pubmed/36397272 http://dx.doi.org/10.1017/S0950268822001807 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
spellingShingle Original Paper
Fantaye, Abayneh Kebede
Goshu, Masitawal Demsie
Zeleke, Berhanu Belay
Gessesse, Adane Abebaw
Endalew, Mehari Fentahun
Birhanu, Zerihun Kinfe
Mathematical model and stability analysis on the transmission dynamics of skin sores
title Mathematical model and stability analysis on the transmission dynamics of skin sores
title_full Mathematical model and stability analysis on the transmission dynamics of skin sores
title_fullStr Mathematical model and stability analysis on the transmission dynamics of skin sores
title_full_unstemmed Mathematical model and stability analysis on the transmission dynamics of skin sores
title_short Mathematical model and stability analysis on the transmission dynamics of skin sores
title_sort mathematical model and stability analysis on the transmission dynamics of skin sores
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987028/
https://www.ncbi.nlm.nih.gov/pubmed/36397272
http://dx.doi.org/10.1017/S0950268822001807
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