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Sexual dimorphism in reactive oxygen species production and a role for integrin α1β1 in estrogen receptor α and β expression in articular cartilage

BACKGROUND: Osteoarthritis (OA) is a debilitating disease involving cartilage degradation. A need remains for the discovery of new molecular targets in cartilage for pharmaceutical intervention of OA. One potential target is integrin α1β1 that protects against OA when it is upregulated by chondrocyt...

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Detalles Bibliográficos
Autores principales: Black, Alicia L., Haskins, James, Pozzi, Ambra, Clark, Andrea L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987067/
https://www.ncbi.nlm.nih.gov/pubmed/36879303
http://dx.doi.org/10.1186/s13018-023-03655-2

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