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PABPN1 regulates mRNA alternative polyadenylation to inhibit bladder cancer progression
BACKGROUND: About 10–20% of patients with bladder cancer (BC) progress to muscle-invasive diseases, of which the underlying key molecular events have yet to be addressed. RESULTS: Here, we identified poly(A) binding protein nuclear 1 (PABPN1), a general factor of alternative polyadenylation (APA), w...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987104/ https://www.ncbi.nlm.nih.gov/pubmed/36879298 http://dx.doi.org/10.1186/s13578-023-00997-6 |