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PABPN1 regulates mRNA alternative polyadenylation to inhibit bladder cancer progression

BACKGROUND: About 10–20% of patients with bladder cancer (BC) progress to muscle-invasive diseases, of which the underlying key molecular events have yet to be addressed. RESULTS: Here, we identified poly(A) binding protein nuclear 1 (PABPN1), a general factor of alternative polyadenylation (APA), w...

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Detalles Bibliográficos
Autores principales: Chen, Liang, Dong, Wei, Zhou, Menghao, Yang, Chenlu, Xiong, Ming, Kazobinka, Gallina, Chen, Zhaohui, Xing, Yifei, Hou, Teng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987104/
https://www.ncbi.nlm.nih.gov/pubmed/36879298
http://dx.doi.org/10.1186/s13578-023-00997-6