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Design, synthesis, molecular docking studies and biological evaluation of thiazole carboxamide derivatives as COX inhibitors

BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) have been the most commonly used class of medications worldwide for the last three decades. OBJECTIVES: This study aimed to design and synthesize a novel series of methoxyphenyl thiazole carboxamide derivatives and evaluate their cyclooxygena...

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Detalles Bibliográficos
Autores principales: Hawash, Mohammed, Jaradat, Nidal, Abualhasan, Murad, Şüküroğlu, Murat Kadır, Qaoud, Mohammed T., Kahraman, Deniz Cansen, Daraghmeh, Heba, Maslamani, Leen, Sawafta, Mais, Ratrout, Ala, Issa, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987136/
https://www.ncbi.nlm.nih.gov/pubmed/36879343
http://dx.doi.org/10.1186/s13065-023-00924-3