Cargando…
Design, synthesis, molecular docking studies and biological evaluation of thiazole carboxamide derivatives as COX inhibitors
BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) have been the most commonly used class of medications worldwide for the last three decades. OBJECTIVES: This study aimed to design and synthesize a novel series of methoxyphenyl thiazole carboxamide derivatives and evaluate their cyclooxygena...
Autores principales: | Hawash, Mohammed, Jaradat, Nidal, Abualhasan, Murad, Şüküroğlu, Murat Kadır, Qaoud, Mohammed T., Kahraman, Deniz Cansen, Daraghmeh, Heba, Maslamani, Leen, Sawafta, Mais, Ratrout, Ala, Issa, Linda |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987136/ https://www.ncbi.nlm.nih.gov/pubmed/36879343 http://dx.doi.org/10.1186/s13065-023-00924-3 |
Ejemplares similares
-
New Thiazole Carboxamide Derivatives as COX Inhibitors:
Design, Synthesis, Anticancer Screening, In Silico Molecular Docking,
and ADME Profile Studies
por: Hawash, Mohammed, et al.
Publicado: (2023) -
Anticancer Activity of Thiophene Carboxamide Derivatives as CA-4 Biomimetics: Synthesis, Biological Potency, 3D Spheroid Model, and Molecular Dynamics Simulation
por: Hawash, Mohammed, et al.
Publicado: (2022) -
Ephedra alata fruit extracts: phytochemical screening, anti-proliferative activity and inhibition of DPPH, α-amylase, α-glucosidase, and lipase enzymes
por: Jaradat, Nidal, et al.
Publicado: (2021) -
Molecular docking, chemo-informatic properties, alpha-amylase, and lipase inhibition studies of benzodioxol derivatives
por: Hawash, Mohammed, et al.
Publicado: (2021) -
Biological Evaluation
of Xanthene and Thioxanthene
Derivatives as Antioxidant, Anticancer, and COX Inhibitors
por: Abualhasan, Murad, et al.
Publicado: (2023)