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A Rare Tumor in a Rare Location: Radiology and Pathology Findings With a Literature Review on Intraventricular Gliosarcoma

Gliosarcoma (GS) is an extraordinarily rare variant of glioblastoma, which is differentiated by its distinct biphasic histopathological morphology consisting of both glial and mesenchymal elements. Although GS has a predilection for the cortical hemispheres, rare occurrences of intraventricular glio...

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Autores principales: Mirchia, Kavya, Mahoney, Mary T, Christie, Omari, Fuller, Christine E, Mirchia, Kanish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987255/
https://www.ncbi.nlm.nih.gov/pubmed/36891012
http://dx.doi.org/10.7759/cureus.34622
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author Mirchia, Kavya
Mahoney, Mary T
Christie, Omari
Fuller, Christine E
Mirchia, Kanish
author_facet Mirchia, Kavya
Mahoney, Mary T
Christie, Omari
Fuller, Christine E
Mirchia, Kanish
author_sort Mirchia, Kavya
collection PubMed
description Gliosarcoma (GS) is an extraordinarily rare variant of glioblastoma, which is differentiated by its distinct biphasic histopathological morphology consisting of both glial and mesenchymal elements. Although GS has a predilection for the cortical hemispheres, rare occurrences of intraventricular gliosarcoma (IVGS) have been documented in the literature. In this report, we present a 68-year-old female patient with a primary IVGS arising from the frontal horn of the left ventricle with corresponding left ventricular entrapment. The clinical course as well as associated tumor features as observed on computed tomography (CT), magnetic resonance imaging (MRI), and immunohistochemical studies are presented along with a relevant review of the current literature.
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spelling pubmed-99872552023-03-07 A Rare Tumor in a Rare Location: Radiology and Pathology Findings With a Literature Review on Intraventricular Gliosarcoma Mirchia, Kavya Mahoney, Mary T Christie, Omari Fuller, Christine E Mirchia, Kanish Cureus Pathology Gliosarcoma (GS) is an extraordinarily rare variant of glioblastoma, which is differentiated by its distinct biphasic histopathological morphology consisting of both glial and mesenchymal elements. Although GS has a predilection for the cortical hemispheres, rare occurrences of intraventricular gliosarcoma (IVGS) have been documented in the literature. In this report, we present a 68-year-old female patient with a primary IVGS arising from the frontal horn of the left ventricle with corresponding left ventricular entrapment. The clinical course as well as associated tumor features as observed on computed tomography (CT), magnetic resonance imaging (MRI), and immunohistochemical studies are presented along with a relevant review of the current literature. Cureus 2023-02-04 /pmc/articles/PMC9987255/ /pubmed/36891012 http://dx.doi.org/10.7759/cureus.34622 Text en Copyright © 2023, Mirchia et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Mirchia, Kavya
Mahoney, Mary T
Christie, Omari
Fuller, Christine E
Mirchia, Kanish
A Rare Tumor in a Rare Location: Radiology and Pathology Findings With a Literature Review on Intraventricular Gliosarcoma
title A Rare Tumor in a Rare Location: Radiology and Pathology Findings With a Literature Review on Intraventricular Gliosarcoma
title_full A Rare Tumor in a Rare Location: Radiology and Pathology Findings With a Literature Review on Intraventricular Gliosarcoma
title_fullStr A Rare Tumor in a Rare Location: Radiology and Pathology Findings With a Literature Review on Intraventricular Gliosarcoma
title_full_unstemmed A Rare Tumor in a Rare Location: Radiology and Pathology Findings With a Literature Review on Intraventricular Gliosarcoma
title_short A Rare Tumor in a Rare Location: Radiology and Pathology Findings With a Literature Review on Intraventricular Gliosarcoma
title_sort rare tumor in a rare location: radiology and pathology findings with a literature review on intraventricular gliosarcoma
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987255/
https://www.ncbi.nlm.nih.gov/pubmed/36891012
http://dx.doi.org/10.7759/cureus.34622
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