Two sides of the same coin: the N-terminal and the receptor binding domains of SARS-CoV-2 Spike

The SARS-CoV-2 Spike receptor binding domain and N-terminal domain interact with each other in an intricate mechanism. Mutations modulate the interplay between the Spike and host molecules. This editorial comments on the intricacies of SARS-CoV-2 Spike interactions.

Detalles Bibliográficos
Autores principales: Ciccozzi, Massimo, Pascarella, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2023
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987531/
https://www.ncbi.nlm.nih.gov/pubmed/36896145
http://dx.doi.org/10.2217/fvl-2022-0181
Descripción
Sumario:The SARS-CoV-2 Spike receptor binding domain and N-terminal domain interact with each other in an intricate mechanism. Mutations modulate the interplay between the Spike and host molecules. This editorial comments on the intricacies of SARS-CoV-2 Spike interactions.

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