Cargando…

Two sides of the same coin: the N-terminal and the receptor binding domains of SARS-CoV-2 Spike

The SARS-CoV-2 Spike receptor binding domain and N-terminal domain interact with each other in an intricate mechanism. Mutations modulate the interplay between the Spike and host molecules. This editorial comments on the intricacies of SARS-CoV-2 Spike interactions.

Detalles Bibliográficos
Autores principales: Ciccozzi, Massimo, Pascarella, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987531/
https://www.ncbi.nlm.nih.gov/pubmed/36896145
http://dx.doi.org/10.2217/fvl-2022-0181
_version_ 1784901400615976960
author Ciccozzi, Massimo
Pascarella, Stefano
author_facet Ciccozzi, Massimo
Pascarella, Stefano
author_sort Ciccozzi, Massimo
collection PubMed
description The SARS-CoV-2 Spike receptor binding domain and N-terminal domain interact with each other in an intricate mechanism. Mutations modulate the interplay between the Spike and host molecules. This editorial comments on the intricacies of SARS-CoV-2 Spike interactions.
format Online
Article
Text
id pubmed-9987531
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Future Medicine Ltd
record_format MEDLINE/PubMed
spelling pubmed-99875312023-03-07 Two sides of the same coin: the N-terminal and the receptor binding domains of SARS-CoV-2 Spike Ciccozzi, Massimo Pascarella, Stefano Future Virol Editorial The SARS-CoV-2 Spike receptor binding domain and N-terminal domain interact with each other in an intricate mechanism. Mutations modulate the interplay between the Spike and host molecules. This editorial comments on the intricacies of SARS-CoV-2 Spike interactions. Future Medicine Ltd 2023-03-06 2023-02 /pmc/articles/PMC9987531/ /pubmed/36896145 http://dx.doi.org/10.2217/fvl-2022-0181 Text en © 2023 Future Medicine Ltd https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Editorial
Ciccozzi, Massimo
Pascarella, Stefano
Two sides of the same coin: the N-terminal and the receptor binding domains of SARS-CoV-2 Spike
title Two sides of the same coin: the N-terminal and the receptor binding domains of SARS-CoV-2 Spike
title_full Two sides of the same coin: the N-terminal and the receptor binding domains of SARS-CoV-2 Spike
title_fullStr Two sides of the same coin: the N-terminal and the receptor binding domains of SARS-CoV-2 Spike
title_full_unstemmed Two sides of the same coin: the N-terminal and the receptor binding domains of SARS-CoV-2 Spike
title_short Two sides of the same coin: the N-terminal and the receptor binding domains of SARS-CoV-2 Spike
title_sort two sides of the same coin: the n-terminal and the receptor binding domains of sars-cov-2 spike
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987531/
https://www.ncbi.nlm.nih.gov/pubmed/36896145
http://dx.doi.org/10.2217/fvl-2022-0181
work_keys_str_mv AT ciccozzimassimo twosidesofthesamecointhenterminalandthereceptorbindingdomainsofsarscov2spike
AT pascarellastefano twosidesofthesamecointhenterminalandthereceptorbindingdomainsofsarscov2spike