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Impact of diabetes mellitus and co-morbidities on mortality in patients with COVID-19: A single-center retrospective study
OBJECTIVES: To describe the effect of diabetes mellitus (DM) on clinical outcomes of patients admitted with COVID-19 infection. METHODS: We carried out a single center, observational, retrospective study. We included adult patients with laboratory-confirmed diagnosis of COVID-19 admitted to a tertia...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Saudi Medical Journal
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987682/ https://www.ncbi.nlm.nih.gov/pubmed/36634951 http://dx.doi.org/10.15537/smj.2023.44.1.20220462 |
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author | Sindi, Anees A. Tashkandi, Wail A. Jastaniah, Mohammed W. Bashanfar, Mohammed A. Fakhri, Ahmed F. Alsallum, Fahad S. Alguydi, Hamdan B. Elhazmi, Alyaa Al-Khatib, Talal A. Alawi, Maha M. Abushoshah, Ibrahim |
author_facet | Sindi, Anees A. Tashkandi, Wail A. Jastaniah, Mohammed W. Bashanfar, Mohammed A. Fakhri, Ahmed F. Alsallum, Fahad S. Alguydi, Hamdan B. Elhazmi, Alyaa Al-Khatib, Talal A. Alawi, Maha M. Abushoshah, Ibrahim |
author_sort | Sindi, Anees A. |
collection | PubMed |
description | OBJECTIVES: To describe the effect of diabetes mellitus (DM) on clinical outcomes of patients admitted with COVID-19 infection. METHODS: We carried out a single center, observational, retrospective study. We included adult patients with laboratory-confirmed diagnosis of COVID-19 admitted to a tertiary hospital in Jeddah, Saudi Arabia, from April 2020 to December 2020. Electronic medical records were reviewed for demographics, clinical status, hospital course, and outcome; and they were compared between the patients with or without DM. RESULTS: Out of 198 patients included in the study, 86 (43.4%) were diabetic and 112 (56.5%) were non-diabetic. Majority of the patients were males 139 (70.2%) with a mean age of 54.14±14.89 years. In-hospital mortality rate was higher in diabetic patients than in non-diabetic patients (40 vs. 32; p=0.011). The most common comorbidity was hypertension (n=95, 48%) followed by ischemic heart disease (n=35, 17.7%), chronic kidney disease (n=17, 9.6%), and bronchial asthma (n=10, 5.1%). CONCLUSION: The risk of SARS-CoV-2 infection is higher among diabetic patients; particularly, those with preexisting co-morbidities or geriatric patients. Diabetic patients are prone to a severe clinical course of COVID-19 and a significantly higher mortality rate. |
format | Online Article Text |
id | pubmed-9987682 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Saudi Medical Journal |
record_format | MEDLINE/PubMed |
spelling | pubmed-99876822023-03-07 Impact of diabetes mellitus and co-morbidities on mortality in patients with COVID-19: A single-center retrospective study Sindi, Anees A. Tashkandi, Wail A. Jastaniah, Mohammed W. Bashanfar, Mohammed A. Fakhri, Ahmed F. Alsallum, Fahad S. Alguydi, Hamdan B. Elhazmi, Alyaa Al-Khatib, Talal A. Alawi, Maha M. Abushoshah, Ibrahim Saudi Med J Original Article OBJECTIVES: To describe the effect of diabetes mellitus (DM) on clinical outcomes of patients admitted with COVID-19 infection. METHODS: We carried out a single center, observational, retrospective study. We included adult patients with laboratory-confirmed diagnosis of COVID-19 admitted to a tertiary hospital in Jeddah, Saudi Arabia, from April 2020 to December 2020. Electronic medical records were reviewed for demographics, clinical status, hospital course, and outcome; and they were compared between the patients with or without DM. RESULTS: Out of 198 patients included in the study, 86 (43.4%) were diabetic and 112 (56.5%) were non-diabetic. Majority of the patients were males 139 (70.2%) with a mean age of 54.14±14.89 years. In-hospital mortality rate was higher in diabetic patients than in non-diabetic patients (40 vs. 32; p=0.011). The most common comorbidity was hypertension (n=95, 48%) followed by ischemic heart disease (n=35, 17.7%), chronic kidney disease (n=17, 9.6%), and bronchial asthma (n=10, 5.1%). CONCLUSION: The risk of SARS-CoV-2 infection is higher among diabetic patients; particularly, those with preexisting co-morbidities or geriatric patients. Diabetic patients are prone to a severe clinical course of COVID-19 and a significantly higher mortality rate. Saudi Medical Journal 2023-01 /pmc/articles/PMC9987682/ /pubmed/36634951 http://dx.doi.org/10.15537/smj.2023.44.1.20220462 Text en Copyright: © Saudi Medical Journal https://creativecommons.org/licenses/by/4.0/This is an Open Access journal and articles published are distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC). Readers may copy, distribute, and display the work for non-commercial purposes with the proper citation of the original work. |
spellingShingle | Original Article Sindi, Anees A. Tashkandi, Wail A. Jastaniah, Mohammed W. Bashanfar, Mohammed A. Fakhri, Ahmed F. Alsallum, Fahad S. Alguydi, Hamdan B. Elhazmi, Alyaa Al-Khatib, Talal A. Alawi, Maha M. Abushoshah, Ibrahim Impact of diabetes mellitus and co-morbidities on mortality in patients with COVID-19: A single-center retrospective study |
title | Impact of diabetes mellitus and co-morbidities on mortality in patients with COVID-19: A single-center retrospective study |
title_full | Impact of diabetes mellitus and co-morbidities on mortality in patients with COVID-19: A single-center retrospective study |
title_fullStr | Impact of diabetes mellitus and co-morbidities on mortality in patients with COVID-19: A single-center retrospective study |
title_full_unstemmed | Impact of diabetes mellitus and co-morbidities on mortality in patients with COVID-19: A single-center retrospective study |
title_short | Impact of diabetes mellitus and co-morbidities on mortality in patients with COVID-19: A single-center retrospective study |
title_sort | impact of diabetes mellitus and co-morbidities on mortality in patients with covid-19: a single-center retrospective study |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987682/ https://www.ncbi.nlm.nih.gov/pubmed/36634951 http://dx.doi.org/10.15537/smj.2023.44.1.20220462 |
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