Cargando…

Potent carbonic anhydrase I, II, IX and XII inhibition activity of novel primary benzenesulfonamides incorporating bis-ureido moieties

A novel series of twelve aromatic bis-ureido-substituted benzenesulfonamides was synthesised by conjugation of aromatic aminobenzenesulfonamides with aromatic bis-isocyanates. The obtained bis-ureido-substituted derivatives were tested against four selected human carbonic anhydrase isoforms (hCA I,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tekeli, Tuba, Akocak, Suleyman, Petreni, Andrea, Lolak, Nebih, Çete, Servet, Supuran, Claudiu T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987750/ https://www.ncbi.nlm.nih.gov/pubmed/36880350 http://dx.doi.org/10.1080/14756366.2023.2185762

Ejemplares similares

Discovery of novel 1,3-diaryltriazene sulfonamides as carbonic anhydrase I, II, VII, and IX inhibitors
por: Akocak, Suleyman, et al.
Publicado: (2018)

Discovery of new 6-ureido/amidocoumarins as highly potent and selective inhibitors for the tumour-relevant carbonic anhydrases IX and XII
por: El-Damasy, Ashraf K., et al.
Publicado: (2023)

Synthesis and biological evaluation of histamine Schiff bases as carbonic anhydrase I, II, IV, VII, and IX activators
por: Akocak, Suleyman, et al.
Publicado: (2017)

Discovery of Novel Hydroxyimine-Tethered Benzenesulfonamides as Potential Human Carbonic Anhydrase IX/XII Inhibitors
por: Peerzada, Mudasir Nabi, et al.
Publicado: (2023)

Synthesis of calix[4]azacrown substituted sulphonamides with antioxidant, acetylcholinesterase, butyrylcholinesterase, tyrosinase and carbonic anhydrase inhibitory action
por: Oguz, Mehmet, et al.
Publicado: (2020)

Synthesis and Inhibition Activity Study of Triazinyl-Substituted Amino(alkyl)-benzenesulfonamide Conjugates with Polar and Hydrophobic Amino Acids as Inhibitors of Human Carbonic Anhydrases I, II, IV, IX, and XII
por: Mikulová, Mária Bodnár, et al.
Publicado: (2021)

Potent and Selective Carboxylic Acid Inhibitors of Tumor-Associated Carbonic Anhydrases IX and XII
por: Cau, Ylenia, et al.
Publicado: (2017)

Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivatives
por: Akocak, Suleyman, et al.
Publicado: (2019)

Synthesis of Sulfonamides Incorporating Piperidinyl-Hydrazidoureido and Piperidinyl-Hydrazidothioureido Moieties and Their Carbonic Anhydrase I, II, IX and XII Inhibitory Activity
por: Moi, Davide, et al.
Publicado: (2022)

Organoruthenium(II) complexes of acetazolamide potently inhibit human carbonic anhydrase isoforms I, II, IX and XII
por: Seršen, Sara, et al.
Publicado: (2019)

Benzenesulfonamides Incorporating Hydantoin Moieties Effectively Inhibit Eukaryoticand Human Carbonic Anhydrases
por: Abdoli, Morteza, et al.
Publicado: (2022)

A class of carbonic anhydrase IX/XII – selective carboxylate inhibitors
por: Alhameed, Rakia Abd, et al.
Publicado: (2020)

4-Anilinoquinazoline-based benzenesulfonamides as nanomolar inhibitors of carbonic anhydrase isoforms I, II, IX, and XII: design, synthesis, in-vitro, and in-silico biological studies
por: Nada, Hossam, et al.
Publicado: (2022)

Isocoumarins: a new class of selective carbonic anhydrase IX and XII inhibitors
por: Onyılmaz, Mehmet, et al.
Publicado: (2022)

Indole-Based Hydrazones Containing A Sulfonamide Moiety as Selective Inhibitors of Tumor-Associated Human Carbonic Anhydrase Isoforms IX and XII
por: Demir-Yazıcı, Kübra, et al.
Publicado: (2019)

Synthesis and Human Carbonic Anhydrase I, II, IX, and XII Inhibition Studies of Sulphonamides Incorporating Mono-, Bi- and Tricyclic Imide Moieties
por: Sethi, Kalyan K., et al.
Publicado: (2021)

Investigation on Hydrazonobenzenesulfonamides as Human Carbonic Anhydrase I, II, IX and XII Inhibitors
por: Moi, Davide, et al.
Publicado: (2022)

Selective inhibition of carbonic anhydrase IX and XII by coumarin and psoralen derivatives
por: Meleddu, Rita, et al.
Publicado: (2021)

Novel 8-Substituted Coumarins That Selectively Inhibit Human Carbonic Anhydrase IX and XII
por: Buran, Kerem, et al.
Publicado: (2019)

Open saccharin-based secondary sulfonamides as potent and selective inhibitors of cancer-related carbonic anhydrase IX and XII isoforms
por: D’Ascenzio, Melissa, et al.
Publicado: (2016)

Continued Structural Exploration of Sulfocoumarin as Selective Inhibitor of Tumor-Associated Human Carbonic Anhydrases IX and XII
por: Giovannuzzi, Simone, et al.
Publicado: (2022)

Inhibition of bacterial α-, β- and γ-class carbonic anhydrases with selenazoles incorporating benzenesulfonamide moieties
por: Angeli, Andrea, et al.
Publicado: (2018)

Sulfocoumarins as dual inhibitors of human carbonic anhydrase isoforms IX/XII and of human thioredoxin reductase
por: Krasavin, Mikhail, et al.
Publicado: (2020)

Activation of α-, β-, γ- δ-, ζ- and η- class of carbonic anhydrases with amines and amino acids: a review
por: Akocak, Suleyman, et al.
Publicado: (2019)

3H-1,2-Benzoxaphosphepine 2-oxides as selective inhibitors of carbonic anhydrase IX and XII
por: Pustenko, Aleksandrs, et al.
Publicado: (2022)

Thiosemicarbazide-Substituted Coumarins as Selective Inhibitors of the Tumor Associated Human Carbonic Anhydrases IX and XII
por: Gumus, Arzu, et al.
Publicado: (2022)

Inhibitory activity against carbonic anhydrase IX and XII as a candidate selection criterion in the development of new anticancer agents
por: Krasavin, Mikhail, et al.
Publicado: (2020)

Selenium-analogs based on natural sources as cancer-associated carbonic anhydrase isoforms IX and XII inhibitors
por: Astrain-Redin, Nora, et al.
Publicado: (2023)

Development of novel anilinoquinazoline-based carboxylic acids as non-classical carbonic anhydrase IX and XII inhibitors
por: Elsayed, Zainab M., et al.
Publicado: (2023)

First studies on tumor associated carbonic anhydrases IX and XII monoclonal antibodies conjugated to small molecule inhibitors
por: Testa, Chiara, et al.
Publicado: (2022)

Intrinsic Thermodynamics and Structure Correlation of Benzenesulfonamides with a Pyrimidine Moiety Binding to Carbonic Anhydrases I, II, VII, XII, and XIII
por: Kišonaitė, Miglė, et al.
Publicado: (2014)

S-substituted 2-mercaptoquinazolin-4(3H)-one and 4-ethylbenzensulfonamides act as potent and selective human carbonic anhydrase IX and XII inhibitors
por: El-Azab, Adel S., et al.
Publicado: (2020)

Carbonic Anhydrases II, IX, and XII in Reflux Esophagitis
por: Nortunen, Minna, et al.
Publicado: (2021)

Novel benzofuran-based sulphonamides as selective carbonic anhydrases IX and XII inhibitors: synthesis and in vitro biological evaluation
por: Abdelrahman, Mohamed A., et al.
Publicado: (2019)

Synthesis of an acridine orange sulfonamide derivative with potent carbonic anhydrase IX inhibitory action
por: Bragagni, Marco, et al.
Publicado: (2017)

Aryl derivatives of 3H-1,2-benzoxaphosphepine 2-oxides as inhibitors of cancer-related carbonic anhydrase isoforms IX and XII
por: Balašova, Anastasija, et al.
Publicado: (2023)

Synthesis and biological evaluation of new 3-substituted coumarin derivatives as selective inhibitors of human carbonic anhydrase IX and XII
por: Mahammad Ghouse, Shaik, et al.
Publicado: (2023)

In Silico Identification and Biological Evaluation of Antioxidant Food Components Endowed with Human Carbonic Anhydrase IX and XII Inhibition
por: Costa, Giosuè, et al.
Publicado: (2020)

The Expression of Carbonic Anhydrases II, IX and XII in Brain Tumors
por: Haapasalo, Joonas, et al.
Publicado: (2020)

Synthesis and cytotoxic activities of novel copper and silver complexes of 1,3-diaryltriazene-substituted sulfonamides
por: Canakci, Dilek, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_v9i5bre9r8vjeatqvhfupgs1gc