Diisocyanates influence models of atopic dermatitis through direct activation of TRPA1

We recently used EPA databases to identify that isocyanates, most notably toluene diisocyanate (TDI), were the pollutant class with the strongest spatiotemporal and epidemiologic association with atopic dermatitis (AD). Our findings demonstrated that isocyanates like TDI disrupted lipid homeostasis...

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Detalles Bibliográficos
Autores principales: Yadav, Manoj, Chaudhary, Prem Prashant, D’Souza, Brandon N., Ratley, Grace, Spathies, Jacquelyn, Ganesan, Sundar, Zeldin, Jordan, Myles, Ian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987805/
https://www.ncbi.nlm.nih.gov/pubmed/36877675
http://dx.doi.org/10.1371/journal.pone.0282569

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