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Protein kinase C showcases allosteric control: activation of LRRK1

Allosteric regulation of multi-domain protein kinases provides a common mechanism to acutely control kinase activity. Protein kinase C serves as a paradigm for multi-domain proteins whose activity is exquisitely tuned by interdomain conformational changes that keep the enzyme off in the absence of a...

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Detalles Bibliográficos
Autores principales:	Tovell, Hannah, Newton, Alexandra C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2023
Materias:	Signaling
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987930/ https://www.ncbi.nlm.nih.gov/pubmed/36762701 http://dx.doi.org/10.1042/BCJ20220507

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