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Interactions between amyloid, amyloid precursor protein, and mitochondria

Mitochondrial dysfunction and Aβ accumulation are hallmarks of Alzheimer's disease (AD). Decades of research describe a relationship between mitochondrial function and Aβ production. Amyloid precursor protein (APP), of which Aβ is generated from, is found within mitochondria. Studies suggest Aβ...

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Detalles Bibliográficos
Autor principal: Wilkins, Heather M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987971/
https://www.ncbi.nlm.nih.gov/pubmed/36688439
http://dx.doi.org/10.1042/BST20220518

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