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Evolutionary and cellular analysis of the ‘dark’ pseudokinase PSKH2

Pseudokinases, so named because they lack one or more conserved canonical amino acids that define their catalytically active relatives, have evolved a variety of biological functions in both prokaryotic and eukaryotic organisms. Human PSKH2 is closely related to the canonical kinase PSKH1, which map...

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Detalles Bibliográficos
Autores principales: Byrne, Dominic P., Shrestha, Safal, Daly, Leonard A., Marensi, Vanessa, Ramakrishnan, Krithika, Eyers, Claire E., Kannan, Natarajan, Eyers, Patrick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988210/
https://www.ncbi.nlm.nih.gov/pubmed/36520605
http://dx.doi.org/10.1042/BCJ20220474