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Multimodal brain age estimates relate to Alzheimer disease biomarkers and cognition in early stages: a cross-sectional observational study

BACKGROUND: Estimates of ‘brain-predicted age’ quantify apparent brain age compared to normative trajectories of neuroimaging features. The brain age gap (BAG) between predicted and chronological age is elevated in symptomatic Alzheimer disease (AD) but has not been well explored in presymptomatic A...

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Detalles Bibliográficos
Autores principales:	Millar, Peter R, Gordon, Brian A, Luckett, Patrick H, Benzinger, Tammie LS, Cruchaga, Carlos, Fagan, Anne M, Hassenstab, Jason J, Perrin, Richard J, Schindler, Suzanne E, Allegri, Ricardo F, Day, Gregory S, Farlow, Martin R, Mori, Hiroshi, Nübling, Georg, Bateman, Randall J, Morris, John C, Ances, Beau M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2023
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988262/ https://www.ncbi.nlm.nih.gov/pubmed/36607335 http://dx.doi.org/10.7554/eLife.81869

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