EHD2 overexpression promotes tumorigenesis and metastasis in triple-negative breast cancer by regulating store-operated calcium entry

With nearly all cancer deaths a result of metastasis, elucidating novel pro-metastatic cellular adaptations could provide new therapeutic targets. Here, we show that overexpression of the EPS15-Homology Domain-containing 2 (EHD2) protein in a large subset of breast cancers (BCs), especially the trip...

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Detalles Bibliográficos
Autores principales: Luan, Haitao, Bielecki, Timothy A, Mohapatra, Bhopal C, Islam, Namista, Mushtaq, Insha, Bhat, Aaqib M, Mirza, Sameer, Chakraborty, Sukanya, Raza, Mohsin, Storck, Matthew D, Toss, Michael S, Meza, Jane L, Thoreson, Wallace B, Coulter, Donald W, Rakha, Emad A, Band, Vimla, Band, Hamid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988264/
https://www.ncbi.nlm.nih.gov/pubmed/36625722
http://dx.doi.org/10.7554/eLife.81288

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