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Association of weight-adjusted-waist index with asthma prevalence and the age of first asthma onset in United States adults

OBJECTIVE: The objective of this study was to assess whether the weight-adjusted-waist index(WWI) is associated with the prevalence of asthma and age when first asthma onset appears in US adults. METHODS: For analysis we selected participants from the National Health and Nutrition Examination Survey...

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Detalles Bibliográficos
Autores principales: Yu, Longshan, Chen, Yan, Xu, Ming, Li, Rongfu, Zhang, Juan, Zhu, Shouwei, He, Zongbao, Chen, Mingwei, Wang, Gaosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988541/
https://www.ncbi.nlm.nih.gov/pubmed/36896186
http://dx.doi.org/10.3389/fendo.2023.1116621
Descripción
Sumario:OBJECTIVE: The objective of this study was to assess whether the weight-adjusted-waist index(WWI) is associated with the prevalence of asthma and age when first asthma onset appears in US adults. METHODS: For analysis we selected participants from the National Health and Nutrition Examination Survey(NHANES)database between 2001 and 2018. A dose-response curve was calculated using logistic regression,subgroup analysis,and a dose-response curve. RESULTS: The study included 44480 people over the age of 20,including 6061 reported with asthma, and the increase in asthma prevalence was 15% associated with each unit increase in the WWI, after adjusting for all confounders(odds ratio(OR)=1.15,95% CI:1.11,1.20). The sensitivity analysis was performed by trichotomizing the WWI, and compared to the lowest tertile, the highest tertile WWI group displayed a 29% increase in asthma prevalence(OR=1.29,95% CI:1.19,1.40). A nonlinear correlation was found between the WWI index and the risk of asthma onset, with a threshold saturation effect indicating an inflection point of 10.53 (log-likelihood ratio test, P<0.05), as well as a positive linear correlation with age at first asthma onset. CONCLUSIONS: A higher WWI index was associated with an increased prevalence of asthma and an older age of first asthma onset.