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Association of weight-adjusted-waist index with asthma prevalence and the age of first asthma onset in United States adults

OBJECTIVE: The objective of this study was to assess whether the weight-adjusted-waist index(WWI) is associated with the prevalence of asthma and age when first asthma onset appears in US adults. METHODS: For analysis we selected participants from the National Health and Nutrition Examination Survey...

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Autores principales: Yu, Longshan, Chen, Yan, Xu, Ming, Li, Rongfu, Zhang, Juan, Zhu, Shouwei, He, Zongbao, Chen, Mingwei, Wang, Gaosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988541/
https://www.ncbi.nlm.nih.gov/pubmed/36896186
http://dx.doi.org/10.3389/fendo.2023.1116621
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author Yu, Longshan
Chen, Yan
Xu, Ming
Li, Rongfu
Zhang, Juan
Zhu, Shouwei
He, Zongbao
Chen, Mingwei
Wang, Gaosheng
author_facet Yu, Longshan
Chen, Yan
Xu, Ming
Li, Rongfu
Zhang, Juan
Zhu, Shouwei
He, Zongbao
Chen, Mingwei
Wang, Gaosheng
author_sort Yu, Longshan
collection PubMed
description OBJECTIVE: The objective of this study was to assess whether the weight-adjusted-waist index(WWI) is associated with the prevalence of asthma and age when first asthma onset appears in US adults. METHODS: For analysis we selected participants from the National Health and Nutrition Examination Survey(NHANES)database between 2001 and 2018. A dose-response curve was calculated using logistic regression,subgroup analysis,and a dose-response curve. RESULTS: The study included 44480 people over the age of 20,including 6061 reported with asthma, and the increase in asthma prevalence was 15% associated with each unit increase in the WWI, after adjusting for all confounders(odds ratio(OR)=1.15,95% CI:1.11,1.20). The sensitivity analysis was performed by trichotomizing the WWI, and compared to the lowest tertile, the highest tertile WWI group displayed a 29% increase in asthma prevalence(OR=1.29,95% CI:1.19,1.40). A nonlinear correlation was found between the WWI index and the risk of asthma onset, with a threshold saturation effect indicating an inflection point of 10.53 (log-likelihood ratio test, P<0.05), as well as a positive linear correlation with age at first asthma onset. CONCLUSIONS: A higher WWI index was associated with an increased prevalence of asthma and an older age of first asthma onset.
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spelling pubmed-99885412023-03-08 Association of weight-adjusted-waist index with asthma prevalence and the age of first asthma onset in United States adults Yu, Longshan Chen, Yan Xu, Ming Li, Rongfu Zhang, Juan Zhu, Shouwei He, Zongbao Chen, Mingwei Wang, Gaosheng Front Endocrinol (Lausanne) Endocrinology OBJECTIVE: The objective of this study was to assess whether the weight-adjusted-waist index(WWI) is associated with the prevalence of asthma and age when first asthma onset appears in US adults. METHODS: For analysis we selected participants from the National Health and Nutrition Examination Survey(NHANES)database between 2001 and 2018. A dose-response curve was calculated using logistic regression,subgroup analysis,and a dose-response curve. RESULTS: The study included 44480 people over the age of 20,including 6061 reported with asthma, and the increase in asthma prevalence was 15% associated with each unit increase in the WWI, after adjusting for all confounders(odds ratio(OR)=1.15,95% CI:1.11,1.20). The sensitivity analysis was performed by trichotomizing the WWI, and compared to the lowest tertile, the highest tertile WWI group displayed a 29% increase in asthma prevalence(OR=1.29,95% CI:1.19,1.40). A nonlinear correlation was found between the WWI index and the risk of asthma onset, with a threshold saturation effect indicating an inflection point of 10.53 (log-likelihood ratio test, P<0.05), as well as a positive linear correlation with age at first asthma onset. CONCLUSIONS: A higher WWI index was associated with an increased prevalence of asthma and an older age of first asthma onset. Frontiers Media S.A. 2023-02-20 /pmc/articles/PMC9988541/ /pubmed/36896186 http://dx.doi.org/10.3389/fendo.2023.1116621 Text en Copyright © 2023 Yu, Chen, Xu, Li, Zhang, Zhu, He, Chen and Wang https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Endocrinology
Yu, Longshan
Chen, Yan
Xu, Ming
Li, Rongfu
Zhang, Juan
Zhu, Shouwei
He, Zongbao
Chen, Mingwei
Wang, Gaosheng
Association of weight-adjusted-waist index with asthma prevalence and the age of first asthma onset in United States adults
title Association of weight-adjusted-waist index with asthma prevalence and the age of first asthma onset in United States adults
title_full Association of weight-adjusted-waist index with asthma prevalence and the age of first asthma onset in United States adults
title_fullStr Association of weight-adjusted-waist index with asthma prevalence and the age of first asthma onset in United States adults
title_full_unstemmed Association of weight-adjusted-waist index with asthma prevalence and the age of first asthma onset in United States adults
title_short Association of weight-adjusted-waist index with asthma prevalence and the age of first asthma onset in United States adults
title_sort association of weight-adjusted-waist index with asthma prevalence and the age of first asthma onset in united states adults
topic Endocrinology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988541/
https://www.ncbi.nlm.nih.gov/pubmed/36896186
http://dx.doi.org/10.3389/fendo.2023.1116621
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