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Mevalonate biosynthesis pathway regulates the development and survival of brown adipocytes

The high thermogenic activity of brown adipose tissue (BAT) has received considerable attention. Here, we demonstrated the role of the mevalonate (MVA) biosynthesis pathway in the regulation of brown adipocyte development and survival. The inhibition of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGC...

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Detalles Bibliográficos
Autores principales:	Kwon, Jungin, Yeh, Yu-Sheng, Kawarasaki, Satoko, Minamino, Hiroto, Fujita, Yoshihito, Okamatsu-Ogura, Yuko, Takahashi, Haruya, Nomura, Wataru, Matsumura, Shigenobu, Yu, Rina, Kimura, Kazuhiro, Saito, Masayuki, Inagaki, Nobuya, Inoue, Kazuo, Kawada, Teruo, Goto, Tsuyoshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988578/ https://www.ncbi.nlm.nih.gov/pubmed/36895651 http://dx.doi.org/10.1016/j.isci.2023.106161

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