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Case report: Autopericardial aortic valve replacement and mitral homograft implantation in a patient with ankylosing spondylitis

INTRODUCTION AND IMPORTANCE: Bekhterev's disease, or ankylosing spondylitis (AS), is a chronic inflammatory rheumatic disease closely related to the human leukocyte antigen (HLA)-B27. Cardiac damage in AS occurs in 2–10 % of patients more commonly as aortic insufficiency, aortitis, mitral valve...

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Autores principales: Komarov, R.N., Tkachev, M.I., Ismailbaev, A.M., Nuzhdin, M.D., Savina, V.A., Botashev, A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988661/
https://www.ncbi.nlm.nih.gov/pubmed/36842395
http://dx.doi.org/10.1016/j.ijscr.2023.107911
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author Komarov, R.N.
Tkachev, M.I.
Ismailbaev, A.M.
Nuzhdin, M.D.
Savina, V.A.
Botashev, A.A.
author_facet Komarov, R.N.
Tkachev, M.I.
Ismailbaev, A.M.
Nuzhdin, M.D.
Savina, V.A.
Botashev, A.A.
author_sort Komarov, R.N.
collection PubMed
description INTRODUCTION AND IMPORTANCE: Bekhterev's disease, or ankylosing spondylitis (AS), is a chronic inflammatory rheumatic disease closely related to the human leukocyte antigen (HLA)-B27. Cardiac damage in AS occurs in 2–10 % of patients more commonly as aortic insufficiency, aortitis, mitral valve fibrosis, or cardiac conduction abnormalities. CASE PRESENTATION: In this article we present a clinical case of a 52-year-old female patient with Bekhterev's disease, who underwent aortic valve reconstruction with autopericardium and mitral homograft implantation in mitral position. CLINICAL DISCUSSION: The use of homografts and reconstructive surgeries using autologous materials allow not only avoiding lifelong intake of anticoagulants, but also maintaining hemodynamic profile comparable to that of native valves. CONCLUSION: This clinical case shows that treatment of patients with rheumatic diseases is a complex treatment problem that requires a personalized approach.
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spelling pubmed-99886612023-03-08 Case report: Autopericardial aortic valve replacement and mitral homograft implantation in a patient with ankylosing spondylitis Komarov, R.N. Tkachev, M.I. Ismailbaev, A.M. Nuzhdin, M.D. Savina, V.A. Botashev, A.A. Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Bekhterev's disease, or ankylosing spondylitis (AS), is a chronic inflammatory rheumatic disease closely related to the human leukocyte antigen (HLA)-B27. Cardiac damage in AS occurs in 2–10 % of patients more commonly as aortic insufficiency, aortitis, mitral valve fibrosis, or cardiac conduction abnormalities. CASE PRESENTATION: In this article we present a clinical case of a 52-year-old female patient with Bekhterev's disease, who underwent aortic valve reconstruction with autopericardium and mitral homograft implantation in mitral position. CLINICAL DISCUSSION: The use of homografts and reconstructive surgeries using autologous materials allow not only avoiding lifelong intake of anticoagulants, but also maintaining hemodynamic profile comparable to that of native valves. CONCLUSION: This clinical case shows that treatment of patients with rheumatic diseases is a complex treatment problem that requires a personalized approach. Elsevier 2023-02-01 /pmc/articles/PMC9988661/ /pubmed/36842395 http://dx.doi.org/10.1016/j.ijscr.2023.107911 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Komarov, R.N.
Tkachev, M.I.
Ismailbaev, A.M.
Nuzhdin, M.D.
Savina, V.A.
Botashev, A.A.
Case report: Autopericardial aortic valve replacement and mitral homograft implantation in a patient with ankylosing spondylitis
title Case report: Autopericardial aortic valve replacement and mitral homograft implantation in a patient with ankylosing spondylitis
title_full Case report: Autopericardial aortic valve replacement and mitral homograft implantation in a patient with ankylosing spondylitis
title_fullStr Case report: Autopericardial aortic valve replacement and mitral homograft implantation in a patient with ankylosing spondylitis
title_full_unstemmed Case report: Autopericardial aortic valve replacement and mitral homograft implantation in a patient with ankylosing spondylitis
title_short Case report: Autopericardial aortic valve replacement and mitral homograft implantation in a patient with ankylosing spondylitis
title_sort case report: autopericardial aortic valve replacement and mitral homograft implantation in a patient with ankylosing spondylitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988661/
https://www.ncbi.nlm.nih.gov/pubmed/36842395
http://dx.doi.org/10.1016/j.ijscr.2023.107911
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