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Visualization of α-synuclein trafficking via nanogold labeling and electron microscopy

There is conflicting evidence regarding the mechanisms of α-synuclein internalization, and its trafficking itinerary following cellular entry remains largely unknown. To examine these issues, we describe steps for coupling α-synuclein preformed fibrils (PFFs) to nanogold beads and their subsequent c...

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Detalles Bibliográficos
Autores principales:	Bayati, Armin, Luo, Wen, Del Cid-Pellitero, Esther, Fon, Edward A., Durcan, Thomas M., McPherson, Peter S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988663/ https://www.ncbi.nlm.nih.gov/pubmed/36861831 http://dx.doi.org/10.1016/j.xpro.2023.102113

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