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Multiple Bioenergy-Linked OCT Biomarkers Suggest Greater-Than-Normal Rod Mitochondria Activity Early in Experimental Alzheimer's Disease

PURPOSE: In Alzheimer's disease, central brain neurons show evidence for early hyperactivity. It is unclear if this occurs in the retina, another disease target. Here, we tested for imaging biomarker manifestation of prodromal hyperactivity in rod mitochondria in vivo in experimental Alzheimer&...

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Detalles Bibliográficos
Autores principales: Berkowitz, Bruce A., Podolsky, Robert H., Childers, Karen L., Roberts, Robin, Waseem, Rida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988708/
https://www.ncbi.nlm.nih.gov/pubmed/36867132
http://dx.doi.org/10.1167/iovs.64.3.12

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