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Multiple Bioenergy-Linked OCT Biomarkers Suggest Greater-Than-Normal Rod Mitochondria Activity Early in Experimental Alzheimer's Disease
PURPOSE: In Alzheimer's disease, central brain neurons show evidence for early hyperactivity. It is unclear if this occurs in the retina, another disease target. Here, we tested for imaging biomarker manifestation of prodromal hyperactivity in rod mitochondria in vivo in experimental Alzheimer&...
Autores principales: | Berkowitz, Bruce A., Podolsky, Robert H., Childers, Karen L., Roberts, Robin, Waseem, Rida |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Association for Research in Vision and Ophthalmology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988708/ https://www.ncbi.nlm.nih.gov/pubmed/36867132 http://dx.doi.org/10.1167/iovs.64.3.12 |
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