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A novel molecular imaging probe [(99m)Tc]Tc-HYNIC-FAPI targeting cancer-associated fibroblasts

Fibroblast activation protein (FAP) is higher expressed on cancer-associated fibroblasts (CAFs) in most malignant epithelial neoplasms, which is lower expressed in normal tissues. As a promising small molecular probe, FAP inhibitor (FAPI) shows the specific binding to FAP. This study aimed to explor...

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Detalles Bibliográficos
Autores principales: Jiang, Yanghongyan, Tian, Yaxin, Feng, Bei, Zhao, Tingting, Du, Liang, Yu, Xiaodong, Zhao, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988823/
https://www.ncbi.nlm.nih.gov/pubmed/36879039
http://dx.doi.org/10.1038/s41598-023-30806-6