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A novel molecular imaging probe [(99m)Tc]Tc-HYNIC-FAPI targeting cancer-associated fibroblasts
Fibroblast activation protein (FAP) is higher expressed on cancer-associated fibroblasts (CAFs) in most malignant epithelial neoplasms, which is lower expressed in normal tissues. As a promising small molecular probe, FAP inhibitor (FAPI) shows the specific binding to FAP. This study aimed to explor...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988823/ https://www.ncbi.nlm.nih.gov/pubmed/36879039 http://dx.doi.org/10.1038/s41598-023-30806-6 |